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Merck
CN

BP423

维生素 K 1

British Pharmacopoeia (BP) Reference Standard

别名:

2-甲基-3-植基-1,4-萘醌, 叶绿醌, 植物甲萘醌, 维生素 K1(20)

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关于此项目

经验公式（希尔记法）:
C31H46O2
化学文摘社编号:
84-80-0
分子量:
450.70
EC Number:
201-564-2
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
2568816
MDL number:
MFCD00214063

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产品名称

维生素 K 1, British Pharmacopoeia (BP) Reference Standard

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

InChI key

MBWXNTAXLNYFJB-NKFFZRIASA-N

SMILES string

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

grade

pharmaceutical primary standard

API family

phytomenadione

form

viscous liquid (Clear)

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

refractive index

n20/D 1.527 (lit.)

mp

−20 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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相关类别

Application

Phytomenadione BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Phytomenadione Injection
  • Phytomenadione Tablets

    • General description

    Phytomenadione is a synthetic lipid-soluble forms of vitamin K1, and works as an essential cofactor for the post-translational γ-carboxyglutamate (Gla) residues in several blood coagulation factors. It is used to treat coagulopathies caused by anticoagulant toxicosis.
    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 0.25 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    存储类别

    10 - Combustible liquids

    wgk

    WGK 1

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Papich GM, et al. et al.
    Saunders Handbook of Veterinary Drugs, (4), 637-638 (2016)
    Rapid HPLC assay for the assessment of vitamin K1, A, E and beta-carotene status in children (7-19 years)
    Jakob E and Elmadfa I
    Internat. J. Vit. Nutr. Res., 65(1), 31-35 (1995)
    HPLC-APCI-MS for the determination of vitamin K1 in human plasma: method and clinical application
    Song Q, et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 875(2), 541-545 (2008)

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