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Merck
CN

BP466

氰钴胺

British Pharmacopoeia (BP) Assay Standard

别名:

维生素 B 12, α-(5,6-Dimethylbenzimidazolyl)cyanocobamide, CN-Cbl, Cyanocob(III)alamin, 氰钴胺

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关于此项目

经验公式（希尔记法）:
C63H88CoN14O14P
化学文摘社编号:
68-19-9
分子量:
1355.37
NACRES:
NA.24
UNSPSC Code:
41116107
MDL number:
MFCD00151092
EC Number:
200-680-0
Beilstein/REAXYS Number:
4122889

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产品名称

氰钴胺, British Pharmacopoeia (BP) Assay Standard

InChI key

RMRCNWBMXRMIRW-QJRSUKKJSA-L

InChI

1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1

SMILES string

C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@

grade

pharmaceutical primary standard

API family

cyanocobalamin

form

solid

manufacturer/tradename

BP

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

color

light red

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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相关类别

Application

Cyanocobalamin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cyanocobalamin Tablets
  • Cyanocobalamin Oral Solution

    • General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Cyanocobalamin is a water soluble vitamin, which plays an important role in animal and plant metabolism.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    存储类别

    11 - Combustible Solids

    wgk

    WGK 1

    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Ultramicrodetermination of cyanocobalamin in elemental diet by solid-phase extraction and high-performance liquid chromatography with visible detection
    Iwase H
    Journal of Chromatography A, 590(2), 359-363 (1992)
    Quantitative simultaneous estimation of water-soluble vitamins, Riboflavin, Pyridoxine, Cyanocobalamin and Folic Acid in neutraceutical products by HPLC
    Perveen S, et al.
    The Open Analytical Chemistry Journal, 3, 1-5 (2009)
    Cibele Dal-Fabbro et al.
    Sleep & breathing = Schlaf & Atmung, 18(4), 749-759 (2014-01-28)
    This study aims to compare the effects of a mandibular advancement device (MAD) with continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA) on blood pressure (BP), oxidative stress, and heart rate variability (HRV) in a randomized, crossed-over
    Maxim A Shevtsov et al.
    Journal of biomedical materials research. Part A, 102(9), 3033-3048 (2013-10-12)
    Angio- and osteogenesis following the two-stage (TS) implantation of the skin- and bone-integrated pylon seeded with autologous fibroblasts was evaluated. Two consecutive animal substudies were undertaken: intramedullary subcutaneous implantation (15 rabbits) and a TS transcutaneous implantation (12 rabbits). We observed
    Esko J Wiltshire et al.
    The Journal of pediatrics, 166(2), 319-325 (2014-12-06)
    To determine the effect of polymorphisms in NOS3 and folate pathway enzymes on vascular function and folate status and endothelial response to folate in children with diabetes or obesity. A total of 244 subjects (age 13.8 ± 2.8 years, 125
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