SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
grade
pharmaceutical primary standard
API family
hydrocortisone
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
mp
211-214 °C (lit.)
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
Gene Information
human ... NR3C1(2908)
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General description
本产品由现行药典发布和说明。随附的本产品的所有支持信息，包括SDS和任何产品信息彩页，均遵照现行药典许可而编制和发布。
有关更多信息和支持，请参见现行药典网站。
有关更多信息和支持，请参见现行药典网站。
Application
氢化可的松BP参考标准品设计用于英国药典规定的指定质量测试和检测。
也用于专著，例如：维甲酸、氢化可的松和对苯二酚乳膏 咪康唑和醋酸氢化可的松乳膏 氢化可的松琥珀酸钠注射液 强的松片 咪康唑和氢化可的松乳膏 咪康唑和氢化可的松乳膏 氢化可的松和新霉素乳膏 氢化可的松和克里喹诺软膏 氢化可的松磷酸钠口服液 强的松胃耐药片 氢化可的松磷酸钠 氢化可的松磷酸钠注射液 氢化可的松和克里喹诺乳膏 甲基强的松片 醋酸氢化可的松口服混悬液 氢化可的松乳膏 氢化可的松口腔黏膜片
也用于专著，例如：
Biochem/physiol Actions
肾上腺皮质分泌的原始糖皮质激素。
肾上腺皮质分泌的原始糖皮质激素。它的抗炎效力是皮质酮的三倍，但 Na2+ 保留效力要低得多。
Other Notes
可能适用相应的销售限制。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
target_organs
Adrenal gland,Bone marrow
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Karin E Koopman et al.
Hepatology (Baltimore, Md.), 60(2), 545-553 (2014-03-29)
American children consume up to 27% of calories from high-fat and high-sugar snacks. Both sugar and fat consumption have been implicated as a cause of hepatic steatosis and obesity but the effect of meal pattern is largely understudied. We hypothesized
Florian Hardeveld et al.
Psychoneuroendocrinology, 50, 62-71 (2014-09-03)
Although HPA-axis activity has been studied extensively in relation to depression, there is no consensus whether HPA-axis parameters predicts major depressive disorder (MDD) recurrence. We investigated whether HPA-axis parameters (cortisol awakening response (CAR), the dexamethasone suppression test (DST) and evening
Lorenz Goette et al.
Psychoneuroendocrinology, 54, 115-123 (2015-02-24)
Social competition is a fundamental mechanism of evolution and plays a central role in structuring individual interactions and communities. Little is known about the factors that affect individuals' competitive success, particularly in humans. Key factors might include stress, a major
Mario Cioce et al.
Oncotarget, 5(12), 4129-4143 (2014-07-02)
Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDHbright cells) and their response to metformin, a promising anticancer metabolic modulator.
Liselotte van Bloemendaal et al.
Diabetes, 63(12), 4186-4196 (2014-07-30)
Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in
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