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BP587

丙酸氟替卡松

British Pharmacopoeia (BP) Reference Standard

别名:

(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester

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关于此项目

经验公式(希尔记法):
C25H31F3O5S
化学文摘社编号:
分子量:
500.57
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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grade

pharmaceutical primary standard

API family

fluticasone

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF

InChI

1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1

InChI key

WMWTYOKRWGGJOA-CENSZEJFSA-N

Gene Information

human ... NR3C1(2908)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fluticasone propionate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Fluticasone and Salmeterol Inhalation Powder
  • Fluticasone and Salmeterol Inhalation Powder, pre-metered
  • Fluticasone Nasal Spray
  • Fluticasone and Salmeterol Pressurised Inhalation, Suspension
  • Fluticasone Pressurised Inhalation
  • Fluticasone Nasal Drops
  • Fluticasone Cream
  • Fluticasone Inhalation Powder
  • Fluticasone Ointment
  • Fluticasone Inhalation Powder, pre-metered
  • Biochem/physiol Actions

    Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.


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    象形图

    Health hazard

    警示词

    Warning

    危险代码

    Hazard Classifications

    Repr. 2 - STOT RE 2

    靶器官

    Endocrine system

    存储类别

    11 - Combustible Solids

    闪点 (F)

    Not applicable

    闪点 (°C)

    Not applicable



    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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