产品名称
乙酰半胱氨酸, British Pharmacopoeia (BP) Reference Standard
InChI key
PWKSKIMOESPYIA-BYPYZUCNSA-N
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
SMILES string
CC(=O)N[C@@H](CS)C(O)=O
grade
pharmaceutical primary standard
API family
acetylcysteine
form
crystalline
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
mp
106-108 °C (lit.)
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
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Application
乙酰半胱氨酸BP参考标准品设计用于英国药典规定的实验室测试。
还用于以下专论：乙酰半胱氨酸滴眼液
还用于以下专论：
Biochem/physiol Actions
抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡，但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。
General description
本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息小册子，均由药典颁发机构制定和发布。如需进一步的信息和支持，请访问药典发布网站。
Other Notes
可能适用相应的销售限制。
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).
Packaging
单位数量：200 mg。可进行调整。本品按照现行药典要求提供。有关当前的单位数量，请访问英国药典
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Hongge Wang et al.
Oncogene, 39(14), 2905-2920 (2020-02-08)
PARP1 and PARP2 play critical roles in regulating DNA repair and PARP inhibitors have been approved for the treatment of BRCA1/2-mutated ovarian and breast cancers. It has long been known that PARP inhibition sensitizes cancer cells to DNA-damaging cytotoxic agents
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