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Merck
CN

C0455000

羧苄青霉素钠

European Pharmacopoeia (EP) Reference Standard

别名:

羧苄青霉素 二钠盐, α-Carboxybenzylpenicillin disodium salt 二钠盐

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关于此项目

经验公式(希尔记法):
C17H16N2Na2O6S
化学文摘社编号:
分子量:
422.36
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5722128
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产品名称

羧苄青霉素钠, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

SMILES string

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

grade

pharmaceutical primary standard

API family

carbenicillin

manufacturer/tradename

EDQM

solubility

H2O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

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Analysis Note

在 37°C 下可稳定保存 3 天

Biochem/physiol Actions

作用机制:羧青霉素抗生素,可通过灭活细菌细胞膜内表面的转肽酶来抑制细菌细胞壁合成(肽聚糖交联)。


抗微生物谱:具有抗革兰氏阳性和革兰氏阴性细菌活性。

Application

Carbenicillin sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Molahlehi S Sonopo et al.
Journal of labelled compounds & radiopharmaceuticals, 58(2), 23-29 (2015-02-19)
A potential anti-TB compound bearing a nitroimidazole moiety from iThemba Pharmaceuticals TB chemical library exhibits promising in vitro activity in the microplate almar blue assay (MABA) with a minimum inhibitory concentration (MIC) value of 3 µg/mL. It is equipotent to the

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