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Merck
CN

C0675000

Cephalexin monohydrate

European Pharmacopoeia (EP) Reference Standard

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关于此项目

经验公式(希尔记法):
C16H17N3O4S · H2O
化学文摘社编号:
分子量:
365.40
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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产品名称

Cephalexin monohydrate, European Pharmacopoeia (EP) Reference Standard

SMILES string

S1[C@H]2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O

InChI

1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1

InChI key

AVGYWQBCYZHHPN-CYJZLJNKSA-N

grade

pharmaceutical primary standard

API family

cephalexin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Cephalexin monohydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Daniela Peneda Pacheco et al.
Journal of materials chemistry. B, 7(32), 4940-4952 (2019-08-15)
Mucus is a natural barrier with a protective role that hinders drug diffusion, representing a steric and interactive barrier to overcome for an effective drug delivery to target sites. In diseases like cystic fibrosis (CF), pulmonary mucus exhibits altered features
Jin Yang et al.
Journal of hazardous materials, 360, 481-489 (2018-08-26)
Photocatalytic ozonation has great potential in wastewater treatment. However, the role of ozone and the contribution of photogenerated hole in this process have not been fully understood. Here three WO3 materials are synthesized and used as model catalysts in visible-light
Ali Rayegan et al.
International journal of biological macromolecules, 113, 317-328 (2018-02-27)
A novel drug delivery system, loaded the drug cephalexin on the basil seed mucilage coated magnetic nanoparticles (Fe3O4@BSM-CPX) was prepared and characterized by means of X-ray diffraction (XRD), Furier Transform Infrared (FTIR), Field Emission Scanning Electron Microscope (FESEM), Vibrating Sample
C W Derrick et al.
Postgraduate medical journal, 59 Suppl 5, 43-46 (1983-01-01)
Cephalexin remains an effective and highly useful antibiotic for the treatment of streptococcal and staphylococcal skin infections. Twelve years of experience have not diminished its efficacy, and cure rates of 90% or higher continue to be achieved. Its resistance to
Gerlinde F Plöger et al.
Journal of pharmaceutical sciences, 109(6), 1846-1862 (2020-04-03)
Literature data and results of experimental studies relevant to the decision to allow waiver of bioequivalence studies in humans for the approval of immediate release solid oral dosage forms containing cephalexin monohydrate are presented. Solubility studies were performed in accordance

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