Merck
CN

C1540000

氯己定 二盐酸盐

European Pharmacopoeia (EP) Reference Standard

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别名:
1,6-双(N5-[对氯苯基]-N1-双胍)己烷;1,1′-己基双(5-[对氯苯基]双胍), 洗必泰
经验公式(希尔记法):
C22H30Cl2N10 · 2HCl
CAS号:
分子量:
578.37
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

chlorhexidine

制造商/商品名称

EDQM

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H

InChI key

WJLVQTJZDCGNJN-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Chlorhexidine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Rengin Attin et al.
Australian orthodontic journal, 29(1), 52-57 (2013-06-22)
The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in highlevel MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement. The subjects of this single-blinded clinical trial
Third-degree chemical burns from chlorhexidine local antisepsis.
Ezequiel Palmanovich et al.
The Israel Medical Association journal : IMAJ, 15(6), 323-324 (2013-07-26)
[Preoperative chlorhexidine shower--unscientific advice from the Swedish Association of Local Authorities and Regions].
Christer Drott
Lakartidningen, 110(16), 836-836 (2013-05-31)
Nicole A Weitz et al.
JAMA dermatology, 149(2), 195-199 (2013-04-06)
Chlorhexidine gluconate-impregnated dressings have become widely adopted as a means to reduce the risk for catheter-associated bloodstream infections. These dressings release antiseptic under occlusion onto the skin surrounding catheter insertion sites. Although chlorhexidine gluconate is a known cause of contact
Claudius Gmür et al.
Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 123(5), 394-409 (2013-05-31)
Five to ten percent of all hospitalized patients are treated in intensive care units. The risk of nosocomial infections is inherent in the latter, especially in cases of intubation. In this context, impaired oral hygiene may play a pivotal role.

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