C1800000
氯苯那敏
European Pharmacopoeia (EP) Reference Standard
别名:
(±)-氯苯那敏 马来酸盐
等级
pharmaceutical primary standard
API类
chlorpheniramine
制造商/商品名称
EDQM
mp
130-135 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
InChI
1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
DBAKFASWICGISY-BTJKTKAUSA-N
基因信息
human ... HRH1(3269)
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Chlorphenamine maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
H 1 组胺受体拮抗剂。
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Eef L Theunissen et al.
British journal of clinical pharmacology, 61(1), 79-86 (2006-01-05)
Previous studies have demonstrated that the antihistamines mequitazine, cetirizine and dexchlorpheniramine produce mild sedation after single doses. It is unknown, however, whether acute sedation persists after repeated dosing. Therefore, this study assessed the effects of repeated dosing of these antihistamines
Anaphylactic reaction to ranitidine and dexchlorpheniramine.
C Thurot-Guillou et al.
European journal of dermatology : EJD, 17(2), 170-171 (2007-03-06)
Urticaria due to aloe vera: a new sensitizer?
Alberto Alvarez-Perea et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 105(5), 404-405 (2010-11-09)
Matthieu Lafaurie et al.
Annales de medecine interne, 154(3), 179-180 (2003-08-12)
Drug-induced aseptic meningitis has been reported mainly with the use of nonsteroidal anti-inflammatory drugs, antibiotics, intravenous immunoglobulins and OKT3 antibodies. We describe today a very unusual reaction on intravenous dexchlorpheniramine with this case of aseptic meningitis.
José R Villada et al.
Journal of cataract and refractive surgery, 31(3), 620-621 (2005-04-07)
We report a severe anaphylactic reaction that occurred about 5 minutes after 1.0 mg of cefuroxime was injected into the anterior chamber after routine phacoemulsification and intraocular lens implantation. The patient was known to be allergic to penicillin. Immediate action
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