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Merck
CN

C2219000

柠檬酸 一水合物

European Pharmacopoeia (EP) Reference Standard

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线性分子式:
HOC(COOH)(CH2COOH)2 · H2O
化学文摘社编号:
分子量:
210.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4018641
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InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

SMILES string

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI key

YASYEJJMZJALEJ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

agency

EP Reference Standard

API family

citric acid

manufacturer/tradename

EDQM

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

application(s)

pharmaceutical (small molecule)

format

neat

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Citric acid monohydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

345.0 °F - closed cup

flash_point_c

173.9 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Katja Sundström et al.
Endocrinology, 155(12), 4798-4807 (2014-09-23)
The growth-promoting effect of combined therapy with GH and IGF-I in normal rats is not known. We therefore investigated the efficacy of treatment with recombinant human (rh)GH and/or rhIGF-I on longitudinal bone growth and bone mass in intact, prepubertal, female
Anne Marie V Schou-Pedersen et al.
Journal of pharmaceutical and biomedical analysis, 107, 333-340 (2015-02-04)
Concentrated solutions containing 6-aminocaproic acid and the excipients citric acid and sorbitol have been studied at temperatures of 50°C, 60°C, 70°C and 80°C as well as at 20°C. It has previously been reported that the commonly employed citric acid is
Leila Bagheri et al.
Journal of microencapsulation, 31(7), 636-643 (2014-04-29)
Whey proteins were inter-connected either by the enzyme transglutaminase or citric acid and then desolvated with ethanol to generate particles. Both samples comprised of sub-micron (>300 nm) and nano-scaled (~100 nm) particles based on the hydrodynamic size measurements. Enzyme-induced cross-linking
Anne R Tinning et al.
American journal of physiology. Renal physiology, 307(11), F1215-F1226 (2014-10-24)
Both the processing and release of secretory granules involve water movement across granule membranes. It was hypothesized that the water channel aquaporin (AQP)1 directly contributes to the recruitment of renin-positive cells in the afferent arteriole. AQP1(-/-) and AQP1(+/+) mice were
C Riemenschneider et al.
Bioresource technology, 170, 303-309 (2014-08-26)
A new analytical method for the determination of colistin in fermenter samples was developed followed by a study on the behavior of this substance during anaerobic fermentation. Analysis of colistin A and B was carried out by liquid chromatography-tandem mass

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