SMILES string
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
InChI key
AKUJBENLRBOFTD-RPRRAYFGSA-N
InChI
1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
biological source
synthetic
grade
pharmaceutical primary standard
agency
EP
API family
dexamethasone
packaging
pkg of 150 mg
manufacturer/tradename
EDQM
storage condition
protect from light
color
white
solubility
water: <0.1 g/L
application(s)
pharmaceutical (small molecule)
format
neat
shipped in
ambient
Gene Information
human ... NR3C1(2908)
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signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
涉药品监管产品
此项目有
Dexamethasone acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 10(3), 4963-4965 (2021)
Textbook of Veterinary Internal Medicine, 87-92 (2009)
Determination of dexamethasone acetate in cream by HPLC.
Garcia CV, et al.
Journal of Pharmaceutical and Biomedical Analysis, 31(3), 597-600 (2003)
Qing-yu Xiang et al.
Archives of pharmacal research, 30(4), 519-525 (2007-05-11)
The objective of the present study was to develop a novel solid lipid nanoparticle (SLN) for the lung-targeting delivery of dexamethasone acetate (DXM) by intravenous administration. DXM loaded SLN colloidal suspensions were prepared by the high pressure homogenization method. The
Zhao-xiong Zhou et al.
Acta pharmacologica Sinica, 30(11), 1577-1584 (2009-11-06)
To investigate the in vitro release profile of drugs encapsulated within perfluorocarbon (PFC) nanoparticles (NPs) and their ability to inhibit the activity of vascular smooth muscle cells (SMCs). Dexamethasone phosphate (DxP) or dexamethasone acetate (DxA) was encapsulated into PFC nanoparticles
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