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文件

D2954000

多巴酚丁胺 盐酸盐

European Pharmacopoeia (EP) Reference Standard

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别名:
(±)-3,4-二羟基-N-[3-(4-羟基苯基)-1-甲基丙基]-β-苯乙胺 盐酸盐
经验公式（希尔记法）:
C18H23NO3 · HCl
CAS号:
49745-95-1
分子量:
337.84
MDL编号:
MFCD00153795
PubChem化学物质编号:
329798764
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

dobutamine

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2

InChI

1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

InChI key

BQKADKWNRWCIJL-UHFFFAOYSA-N

基因信息

human ... ADRB1(153) , ADRB2(154)

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Dobutamine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation markHealth hazard
GHS07,GHS08

警示用语：

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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Neeraj Singh et al.
Transplantation, 94(12), 1224-1229 (2012-12-25)
The utility of cardiac stress testing as a risk-stratification tool before kidney transplantation remains debatable owing to discordance with coronary angiography and outcome yields at different centers. We conducted a retrospective study of 273 diabetic kidney transplant recipients from 2006
Kiril A Ahtarovski et al.
American journal of physiology. Heart and circulatory physiology, 305(7), H1098-H1103 (2013-07-03)
Men and women are known to react differently to stress. Thus, stress cardiomyopathy almost solely strikes women. Stress cardiomyopathy is suggested to relate to sex differences in catecholamine reaction. Left heart function during dobutamine stress is well described, but sex-specific
Edmund M T Lau et al.
Chest, 146(4), 959-966 (2014-03-15)
Stress testing of the pulmonary circulation (via increasing pulmonary blood flow) can reveal abnormal mean pulmonary artery pressure-cardiac output (mPpa-Q) responses, which may facilitate early diagnosis of pulmonary vascular disease. We investigated the application of dobutamine stress echocardiography (DSE) for
X Monnet et al.
British journal of anaesthesia, 111(5), 743-749 (2013-06-27)
We tested the ability of mean acceleration (Acc) and peak velocity (V peak) of the aortic velocity signal measured by oesophageal Doppler to reflect left ventricular (LV) systolic performance. We included critically ill patients in whom a fluid challenge (n=25)
Martin G Schultz et al.
American journal of hypertension, 26(4), 557-566 (2013-03-08)
The J-curve relationship between brachial diastolic blood pressure (DBP) and mortality is believed to be mediated through reduced myocardial perfusion. This study aimed to determine the relationship between DBP and subendocardial perfusion in patients with and without coronary artery disease
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