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Merck
CN

E1100000

麦角甾醇

European Pharmacopoeia (EP) Reference Standard

别名:

(3β)-麦角-5,7,22-三烯甘油-3-醇, 3β-羟基-5,7,22-麦角三烯, 维生素原 D2

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关于此项目

经验公式(希尔记法):
C28H44O
化学文摘社编号:
分子量:
396.65
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2338604
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产品名称

麦角甾醇, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1

SMILES string

[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C

InChI key

DNVPQKQSNYMLRS-APGDWVJJSA-N

biological source

plant

grade

pharmaceutical primary standard

agency

EP

API family

ergosterol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

156-158 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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Application

麦角固醇可用作药物参考标准品,用于通过液相色谱测定药物制剂中的分析物。

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。
麦角固醇是在存在于真菌细胞膜和某些原生生物(如锥虫)中的维生素D2的生物前体。

Other Notes

可能适用相应的销售限制。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

hcodes

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ergocalciferol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 54(12), 6604-6606 (201)
Analysis of ergosterol in single kernel and ground grain by gas chromatography- mass spectrometry
Dong Y, et al.
Journal of Agricultural and Food Chemistry, 54(12), 4121-4125 (2006)
Cetin Kadakal et al.
Critical reviews in food science and nutrition, 44(5), 349-351 (2004-11-16)
The poor precision of the "percentage of discarded fruits" and "Howard mold count" methods has increased the importance of ergosterol for the microbiological quality evaluation of tomato and tomato products. Ergosterol, a constituent of the cell wall of some important
Yong-Qiang Zhang et al.
Virulence, 1(6), 551-554 (2010-12-24)
Many antifungal drugs including the highly successful azoles target the fungal-specific sterol, ergosterol, yet the molecular identity of cellular pathways mediating antifungal activity remained obscure. A recent study on the requirement of ergosterol in vacuolar H+-ATPase (V-ATPase) function uncovered a
Mario Ruiz et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1555-1567 (2013-12-24)
Lipocalins are small extracellular proteins mostly described as lipid carriers. The Drosophila lipocalin NLaz (neural Lazarillo) modulates the IIS pathway and regulates longevity, stress resistance, and behavior. Here, we test whether a native hydrophobic pocket structure is required for NLaz

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