E1310000
Erythromycin B
European Pharmacopoeia (EP) Reference Standard
别名:
12-Deoxyerythromycin
等级
pharmaceutical primary standard
API类
erythromycin
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
N(C1C(C(OC(C1)C)O[C@H]2[C@@](C[C@H](C(=O)[C@@H]([C@H]([C@H]([C@H](OC(=O)[C@@H]([C@H](C2C)OC3OC(C(C(C3)(OC)C)O)C)C)CC)C)O)C)C)(O)C)O)(C)C
InChI
1S/C37H67NO12/c1-14-26-20(4)29(40)21(5)28(39)18(2)16-36(9,44)33(50-35-30(41)25(38(11)12)15-19(3)46-35)22(6)31(23(7)34(43)48-26)49-27-17-37(10,45-13)32(42)24(8)47-27/h18-27,29-33,35,40-42,44H,14-17H2,1-13H3/t18-,19?,20+,21+,22?,23-,24?,25?,26-,27?,29+,30?,31+,32?,33-,35?,36-,37?/m1/s1
InChI key
IDRYSCOQVVUBIJ-ZTOAHLHUSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Erythromycin B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
免责声明
Sales restrictions may apply.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
涉药品监管产品
此项目有
An abiotic strategy for the enantioselective synthesis of erythromycin B.
Paul J Hergenrother et al.
Angewandte Chemie (International ed. in English), 42(28), 3278-3281 (2003-07-24)
Q Zhang et al.
Letters in applied microbiology, 52(2), 129-137 (2010-12-24)
To overproduce erythromycin C, B or D and evaluate the effect of disruption of tailoring genes eryK and eryG in an industrial erythromycin producer. The tailoring genes eryG and eryK were inactivated individually or simultaneously by targeted gene disruption in
M S Brown et al.
The Journal of antibiotics, 52(8), 742-747 (1999-12-02)
Cyclopropane carboxylic acid was fed to Saccharopolyspora erythraea NRRL 18643 (6-deoxyerythromycin producer), resulting in the production of 6-deoxy-13-cyclopropyl-erythromycin B. These studies provide further evidence that deoxyerythronolide B synthase has a relaxed specificity for the starter unit.
S Morimoto et al.
The Journal of antibiotics, 43(5), 544-549 (1990-05-01)
6-O-Methylerythromycin B has been synthesized from erythromycin B via regioselective methylation of the 6-hydroxyl group in 71% overall yield. This compound shows in vitro antibacterial activity comparable to erythromycins A and B and exhibits superior in vivo activity with improved
Sara Bogialli et al.
Rapid communications in mass spectrometry : RCM, 21(2), 237-246 (2006-12-16)
A rapid and simple sample preparation procedure for determining residues of antibiotics of the class of macrolides and lincomycin in whole milk and yoghurt by liquid chromatography/tandem mass spectrometry (LC/MS/MS) is presented. The method is based on the matrix solid-phase
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