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文件

E2425000

4-羟基苯甲酸乙酯

Name: 4-羟基苯甲酸乙酯
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

尼泊金乙酯

线性分子式:

HOC₆H₄CO₂C₂H₅

CAS号:

120-47-8

分子量:

166.17

Beilstein:

1101972

MDL编号:

MFCD00002353

PubChem化学物质编号:

329799028

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

parabens

制造商/商品名称

EDQM

bp

297-298 °C (lit.)

mp

114-117 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

CCOC(=O)c1ccc(O)cc1

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ethyl parahydroxybenzoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry.

Maw-Rong Lee et al.

Journal of chromatography. A, 1120(1-2), 244-251 (2006-03-04)

This study evaluated supercritical fluid extraction (SFE) combined with liquid chromatography-mass spectrometry (LC-MS) to determine trace preservatives and antioxidants including methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylparaben (BP), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), alpha-tocopherol (alpha-t) and alpha-tocopherol acetate (alpha-ta)

Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex.

Esther Pérez et al.

The Journal of biological chemistry, 279(41), 42584-42592 (2004-08-05)

A few mycobacterial species, most of which are pathogenic for humans, produce dimycocerosates of phthiocerol (DIM) and of glycosylated phenolphthiocerol, also called phenolglycolipid (PGL), two groups of molecules shown to be important virulence factors. The biosynthesis of these molecules is

Ethyl-paraben and nicotinamide mixtures: apparent solubility, thermal behavior and X-ray structure of the 1:1 co-crystal.

S Nicoli et al.

Journal of pharmaceutical sciences, 97(11), 4830-4839 (2008-03-05)

This work aims at investigating the nicotinamide (NA)-ethyl-paraben (EP) binary system both in solution and in the solid state. In particular, the apparent EP solubility in water was studied in the presence of different NA concentrations (between 0.28 and 1.64

Assessment of principal parabens used in cosmetics after their passage through human epidermis-dermis layers (ex-vivo study).

Sawsan El Hussein et al.

Experimental dermatology, 16(10), 830-836 (2007-09-12)

Concern is continuously raised about the safety of parabens which are present in most of the cosmetic preparations. In this investigation, methyl-, ethyl-, propyl- and butyl paraben (MP, EP, PP, BP), in a commercial cosmetic lotion, were deposited on human

Lack of spermatotoxic effects of methyl and ethyl esters of p-hydroxybenzoic acid in rats.

Shinshi Oishi

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1845-1849 (2004-09-08)

Parabens are alkyl esters of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in estrogen receptor assays in vitro. In addition butyl and propyl parabens show

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