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关于此项目
经验公式（希尔记法）:
C22H16F2N2
化学文摘社编号:
分子量:
346.37
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
Fc1c(cccc1)C([n]4cncc4)(c3ccc(cc3)F)c2ccccc2
InChI
1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H
InChI key
QHMWCHQXCUNUAK-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
flutrimazole
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Flutrimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
A Alomar et al.
Dermatology (Basel, Switzerland), 190(4), 295-300 (1995-01-01)
Flutrimazole is a new imidazole derivate. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. To compare the efficacy and tolerability of flutrimazole cream 1%
Synthesis and antifungal activity of a series of difluorotritylimidazoles.
J Bartrolí et al.
Arzneimittel-Forschung, 42(6), 832-835 (1992-06-01)
In vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity.
J García Rafanell et al.
Arzneimittel-Forschung, 42(6), 836-840 (1992-06-01)
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (MIC = 0.025-5.0 micrograms/ml). In most of these
O Binet et al.
Mycoses, 37(11-12), 455-459 (1994-11-01)
In a multicentre, double-blind, randomized, parallel group clinical trial, the efficacy and tolerability of flutrimazole 1% dermal cream were compared with those of a reference compound, clotrimazole 1% dermal cream, applied topically twice daily for 4 weeks in patients with
del Palacio et al.
Mycoses, 38(9-10), 395-403 (1995-09-01)
In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% solution were compared with bifonazole 1% solution, applied once daily for 4 weeks, in 40 patients with culturally proven dermatophytosis or cutaneous candidosis. Forty patients with mycologically proven
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