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Merck
CN

F0700000

呋塞米

European Pharmacopoeia (EP) Reference Standard

别名:

4-氯-N-呋喃基-5-氨磺酰邻氨基苯甲酸, 5-(氨基磺酰基)-4-氯-2-([2-呋喃甲基]氨基)苯甲酸

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关于此项目

经验公式(希尔记法):
C12H11ClN2O5S
化学文摘社编号:
分子量:
330.74
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

呋塞米, European Pharmacopoeia (EP) Reference Standard

InChI key

ZZUFCTLCJUWOSV-UHFFFAOYSA-N

SMILES string

NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl

InChI

1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)

grade

pharmaceutical primary standard

API family

furosemide

manufacturer/tradename

EDQM

mp

220 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SLC12A1(6557)

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Biochem/physiol Actions

抑制肾脏中离子的协同运输。

Application

Furosemide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Carels et al.
JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR), 96(1), 17-18 (2013-04-25)
We report a case of sudden onset of respiratory distress caused by pulmonary edema due to laryngospasm. The diagnosis was established by the clinical context and chest X-ray. A CT-scan was performed to narrow down the differential diagnosis and to
Case scenario: Hemodynamic management of postoperative acute kidney injury.
Matthieu Legrand et al.
Anesthesiology, 118(6), 1446-1454 (2013-04-06)
Xin-Gui Peng et al.
Radiology, 269(3), 748-757 (2013-08-01)
To determine the relationship between renal lipid content and intrarenal oxygenation in diabetic nephropathy by using noninvasive chemical shift-selective (CSS) imaging and blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging. The study was approved by the institutional Committee on Animal
Naoki Sato et al.
Circulation journal : official journal of the Japanese Circulation Society, 77(4), 944-951 (2013-03-19)
Hospitalized heart failure (HHF) is a critical issue in Japan. To improve its management and outcomes, the clinical features, in-hospital management, and outcomes should be analyzed to improve the guidelines for HHF. The acute decompensated heart failure syndromes (ATTEND) registry
Maarten C van Loon et al.
Hearing research, 298, 17-26 (2013-01-31)
It is well known that spiral ganglion cells (SGCs) degenerate in hair-cell-depleted cochleas and that treatment with exogenous neurotrophins can prevent this degeneration. Several studies reported that, in addition, SGC size decreases after deafening and increases after neurotrophic treatment. The

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