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Merck
CN

G0400007

甘油

European Pharmacopoeia (EP) Reference Standard

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关于此项目

经验公式(希尔记法):
C21H40O4
化学文摘社编号:
分子量:
356.54
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

O(CC(O)CO)C(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

grade

pharmaceutical primary standard

API family

glyceryl monooleate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。 如需进一步信息和支持,请访问现行药典网站。

Application

甘油单油酸酯EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Packaging

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

Other Notes

销售限制可能适用。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vikas Jain et al.
Biomaterials, 33(29), 7206-7220 (2012-07-20)
A PEGylated drug delivery system of paclitaxel (PTX), based on glyceryl monooleate (GMO) was prepared by optimizing various parameters to explore its potential in anticancer therapy. The prepared system was characterized through polarized light microscopy, TEM, AFM and SAXS to
Christa Nilsson et al.
Langmuir : the ACS journal of surfaces and colloids, 28(32), 11755-11766 (2012-07-27)
The present study was designed to evaluate the effect of the negatively charged food-grade emulsifier citrem on the internal nanostructures of oil-free and oil-loaded aqueous dispersions of phytantriol (PHYT) and glyceryl monooleate (GMO). To our knowledge, this is the first
Guoliang Zhen et al.
Molecular pharmaceutics, 9(9), 2450-2457 (2012-07-17)
We present studies of the delivery of short interfering ribonucleic acid (siRNA) into a green fluorescent protein (GFP) expressing cell line, using lipid nanocarriers in cubic lyotropic liquid crystal form. These carriers are based on glycerol monooleate (GMO) and employ
Victoria M Steffes et al.
Biomaterials, 145, 242-255 (2017-09-11)
Lipid-based particles are used worldwide in clinical trials as carriers of hydrophobic paclitaxel (PTXL) for cancer chemotherapy, albeit with little improvement over the standard-of-care. Improving efficacy requires an understanding of intramembrane interactions between PTXL and lipids to enhance PTXL solubilization
Chandrashekhar V Kulkarni
Nanoscale, 4(19), 5779-5791 (2012-08-18)
Lipid crystallization is ubiquitous in nature, observed in biological structures as well as in commercial products and applications. In a dehydrated state most of the lipids form well ordered crystals, whereas in an aqueous environment they self-assemble into various crystalline

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