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Merck
CN

H0325000

海克替啶

European Pharmacopoeia (EP) Reference Standard

别名:

海克替啶,立体异构体混合物, 5-氨基-1,3-双(2-乙己基)六氢-5-甲基嘧啶, NSC 17764

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关于此项目

经验公式(希尔记法):
C21H45N3
化学文摘社编号:
分子量:
339.60
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI

1S/C21H45N3/c1-6-10-12-19(8-3)14-23-16-21(5,22)17-24(18-23)15-20(9-4)13-11-7-2/h19-20H,6-18,22H2,1-5H3

SMILES string

CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1

InChI key

DTOUUUZOYKYHEP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

hexetidine

manufacturer/tradename

EDQM

refractive index

n20/D 1.4649 (lit.)

bp

160 °C/0.4 mmHg (lit.)

density

0.889 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

参与研究:
  • 鉴定(identify)阿司匹林的纯液体盐形式
  • 作为基于烷基的选择性置换剂候选,用于离子交换色谱法蛋白纯化
  • 体内应用模型,用于试验非复制结核分枝杆菌抗性药物
  • 将能量代谢从线粒体呼吸转变为糖酵解的药物的营养敏化筛选
  • 血管形成抑制
  • 抗疟药物筛选

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

158.0 °F - closed cup

flash_point_c

70 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Andreas Peyrl et al.
Journal of neuro-oncology, 120(1), 139-145 (2014-07-16)
The Ommaya reservoir facilitates repetitive delivery of drugs into the CSF and is a pharmacologically rational system for intrathecal chemotherapy. Because previous studies have found a high rate of infection and other complications we herein studied our experience with this
Elvedina Kapić et al.
Medicinski arhiv, 56(1), 43-48 (2002-03-29)
Hexetidine is very safe oral antiseptic with broad antibacterial and antifungal activity in vivo and in vitro. It has local-anesthetics, astringent and deodorant activity. Also, it has very strong antiplac effects. Resistention of microorganisms on hexetidine is short and transient.
F Afennich et al.
International journal of dental hygiene, 9(3), 182-190 (2011-03-02)
To review the literature concerning hexetidine-containing mouthwash as a monotherapy or as an adjunct to oral hygiene in the prevention of plaque accumulation and gingival inflammation. PubMed-MEDLINE and the Cochrane-CENTRAL were searched through January 2010 to identify appropriate studies. The
Synergistic antiplaque effects of a zinc fluoride/hexetidine containing mouthwash. A review.
U P Saxer et al.
Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 93(8), 689-704 (1983-08-01)

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