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文件

K2000000

酮洛芬

Name: 酮洛芬
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

2-(3-苯甲酰苯基)丙酸

经验公式（希尔记法）:

C₁₆H₁₄O₃

CAS号:

22071-15-4

分子量:

254.28

MDL编号:

MFCD00055790

PubChem化学物质编号:

329817130

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

ketoprofen

制造商/商品名称

EDQM

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

基因信息

human ... PTGS1(5742) , PTGS2(5743)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Ketoprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

非甾体类抗炎化合物，具有COX-1选择性。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

1356643

1356563

1356552

BP668

酮洛芬, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

2-(3-苯甲酰基苯基)-丙腈, pharmaceutical secondary standard, certified reference material

PHR2955

PHR3018

象形图

GHS06

警示用语：

Danger

危险声明

H301

预防措施声明

P264 - P270 - P301 + P310 - P405 - P501

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release.

Zeting Yuan et al.

International journal of pharmaceutics, 446(1-2), 191-198 (2013-02-21)

Chitosan (CS) grafted with β-cyclodextrin (CD-g-CS) nanoparticles as a new carrier for poorly water-soluble drugs has been developed. The CD-g-CS polymer is readily synthesized from chitosan and mono-6-deoxy-6-(p-toluenesulfonyl)-β-cyclodextrin. Three different degrees of substitution (DS) of β-cyclodextrin (β-CD) on CD-g-CS (9.6

Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.

Yan-Ping Duan et al.

The Science of the total environment, 447, 267-273 (2013-02-09)

The occurrence and multi-phase distribution of five pharmaceutical compounds were investigated in an urban wastewater treatment plant (WWTP) receiving river by analysis of pharmaceuticals in sediment, particulate matter, conventional dissolved phase (>0.7 μm), colloidal phase (5 kDa to 0.7 μm)

Ketoprofen impairs immunosuppression induced by severe sepsis and reveals an important role for prostaglandin E2.

Ariane Rennó Brogliato et al.

Shock (Augusta, Ga.), 38(6), 620-629 (2012-11-13)

The mechanism of immunosuppression induced by severe sepsis is not fully understood. The production of prostaglandin E2 (PGE2) during sepsis is well known, but its role in long-term consequences of sepsis has not been explored. The current study evaluates the

Continuous-flow encapsulation of ketoprofen in copolymer microbeads via co-axial microfluidic device: influence of operating and material parameters on drug carrier properties.

Ikram Ullah Khan et al.

International journal of pharmaceutics, 441(1-2), 809-817 (2012-12-26)

Microchannels based microfluidic systems are able to obtain monodispersed microparticles but are limited by cost, time and channel clogging. We succeeded in on the fly encapsulation of high ketoprofen contents in acrylate-based copolymer microbeads by environment friendly UV induced free

The effect of administering ketoprofen on the physiology and behavior of dairy cows following surgery to correct a left displaced abomasum.

Nathalie C Newby et al.

Journal of dairy science, 96(3), 1511-1520 (2013-01-22)

Surgical correction of left displaced abomasum (LDA) is common in lactating dairy cattle. Despite the growing acceptance that abdominal surgery is painful, few cows are administered analgesia following LDA surgery. The objective of this research was to examine the effect

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酮洛芬