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文件

M0960000

蛋氨酸

Name: 蛋氨酸
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

L-甲硫氨酸, L-2-氨基-4-（甲硫基）丁酸, （S）-2-氨基-4-（甲巯基）丁酸

线性分子式:

CH₃SCH₂CH₂CH(NH₂)CO₂H

CAS号:

63-68-3

分子量:

149.21

Beilstein:

1722294

MDL编号:

MFCD00063097

PubChem化学物质编号:

329817843

NACRES:

NA.24

等级

pharmaceutical primary standard

API family

methionine & derivatives

manufacturer/tradename

EDQM

mp

284 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

格式

neat

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

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一般描述

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

应用

蛋氨酸EP 参考标准品设计用于欧洲药典规定的实验室测试。

包装

本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。

其他说明

可能适用相应的销售限制。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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示例

T1503

货号

25G

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705578-5MG-PW

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The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans.

Ronald O Ball et al.

The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)

Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are

Value of 11C-methionine PET in imaging brain tumours and metastases.

Andor W J M Glaudemans et al.

European journal of nuclear medicine and molecular imaging, 40(4), 615-635 (2012-12-13)

(11)C-methionine (MET) is the most popular amino acid tracer used in PET imaging of brain tumours. Because of its characteristics, MET PET provides a high detection rate of brain tumours and good lesion delineation. This review focuses on the role

Analysis of metabolic profiles of bile acids in urine using a lipophilic anion exchanger and computerized gas-liquid chromatorgaphy-mass spectrometry.

B Almé et al.

Journal of lipid research, 18(3), 339-362 (1977-05-01)

A method is described for quantitative analysis of bile acids in urine. Urine is acidified and bile acids are extracted on an Amberlite XAD-2 column. Bile salts are converted to acids on an Amberlyst A-15 column and are separated into

Planar scintigraphy with 123I/99mTc-sestamibi, 99mTc-sestamibi SPECT/CT, 11C-methionine PET/CT, or selective venous sampling before reoperation of primary hyperparathyroidism?

Camilla Schalin-Jäntti et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(5), 739-747 (2013-04-05)

All patients with primary hyperparathyroidism should undergo localization studies before reoperation, but it is not known which method is most accurate. The purpose of this prospective study was to compare the performance of planar scintigraphy with (123)I/(99m)Tc-sestamibi, (99m)Tc-sestamibi SPECT (SPECT/CT)

Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.

Leen Mathys et al.

PloS one, 9(6), e101181-e101181 (2014-06-27)

N-linked glycans covering the surface of the HIV-1 glycoprotein gp120 are of major importance for the correct folding of this glycoprotein. Of the, on average, 24 N-linked glycans present on gp120, the glycan at Asn260 was reported to be essential

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