M1808000
Metixene hydrochloride
European Pharmacopoeia (EP) Reference Standard
别名:
Methixene monohydrochloride monohydrate
等级
pharmaceutical primary standard
API类
metixene
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
S1c2c(cccc2)C(c4c1cccc4)CC3CN(CCC3)C.[Cl-].O.[H+]
InChI
1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2
InChI key
RAOHHYUBMJLHNC-UHFFFAOYSA-N
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Metixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
M I Walash et al.
Pharmaceutisch weekblad. Scientific edition, 8(4), 234-238 (1986-08-22)
A simple and rapid colorimetric method for the quantitative determination of the thioxanthene derivatives, chlorprothixene, tiotixene and metixene has been performed either in their pure form or in tablets. The procedure is based upon the formation of charge transfer complexes
[An anticholinergic agent, the side effect of mouth dryness and hazards for the teeth].
W H van Palenstein Helderman et al.
Nederlands tijdschrift voor geneeskunde, 127(51), 2318-2321 (1983-12-17)
JAMA, 195(10), 851-851 (1966-03-07)
Methixene hydrochloride, an anticholinergic agent, may be useful in the symptomatic treatment of functional bowel disorders. Adverse effects reported from its use are those of the anticholinergic drugs in general.
P A Fischer et al.
Journal of neural transmission. Supplementum, 25, 137-147 (1987-01-01)
To quantify the clinical benefit of an additional deprenyl administration in L-dopa pretreated patients we have performed a study of 30 patients suffering from advanced parkinsonism. During the first phase of the study over three months under controlled conditions deprenyl
[Treatment of extrapyramidal tremors in the aged].
D Hust
Die Medizinische Welt, 32(19), 743-746 (1981-05-08)
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