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Merck
CN

M1808000

Metixene hydrochloride

European Pharmacopoeia (EP) Reference Standard

别名:

Methixene monohydrochloride monohydrate

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关于此项目

经验公式(希尔记法):
C20H23NSl · HCl · H2O
化学文摘社编号:
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

S1c2c(cccc2)C(c4c1cccc4)CC3CN(CCC3)C.[Cl-].O.[H+]

InChI

1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2

InChI key

RAOHHYUBMJLHNC-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

metixene

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P A Fischer et al.
Journal of neural transmission. Supplementum, 25, 137-147 (1987-01-01)
To quantify the clinical benefit of an additional deprenyl administration in L-dopa pretreated patients we have performed a study of 30 patients suffering from advanced parkinsonism. During the first phase of the study over three months under controlled conditions deprenyl
S L Levin
International journal of clinical pharmacology research, 6(5), 429-439 (1986-01-01)
Dualism in the effects of atropine, and metixene upon the denervated human parotid salivary gland is demonstrated by the fact that they suppress pilocarpine secretion while themselves causing an extremely intense and prolonged salivation. A still stronger cholinolytic, chlorosyle, although
A complication of self-poisoning.
C H Gerrand et al.
Postgraduate medical journal, 73(856), 113-114 (1997-02-01)
[The treatment of Parkinson tremors and forms of extrapyramidal tremors with methixene. A multicenter study].
E Volles et al.
Die Medizinische Welt, 34(24), 707-709 (1983-06-17)
M I Walash et al.
Pharmaceutisch weekblad. Scientific edition, 8(4), 234-238 (1986-08-22)
A simple and rapid colorimetric method for the quantitative determination of the thioxanthene derivatives, chlorprothixene, tiotixene and metixene has been performed either in their pure form or in tablets. The procedure is based upon the formation of charge transfer complexes

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