InChI
1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3
SMILES string
CCN(CC)C(=O)c1cccnc1
InChI key
NCYVXEGFNDZQCU-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
nikethamide
manufacturer/tradename
EDQM
refractive index
n20/D 1.524 (lit.)
bp
296-300 °C (lit.)
mp
23 °C (lit.)
density
1.06 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Nikethamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Determination of nikethamide and N-ethylnicotinamide in the blood and urine of greyhounds.
Lewis J H.
Journal of Chromatography A, 172, 295-302 (1979)
Lili Chen et al.
Journal of pharmaceutical and biomedical analysis, 43(5), 1757-1762 (2007-02-10)
Nikethamide and lidocaine are often requested to be quantified simultaneously in forensic toxicological analysis. A simple reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed for their simultaneous determination in human blood and cerebrospinal fluid. The method involves simple
Nathaly Reyes-Garcés et al.
Journal of chromatography. A, 1374, 40-49 (2014-12-03)
Simple, fast and efficient sample preparation approaches that allow high-throughput isolation of various compounds from complex matrices are highly desired in bioanalysis. Particularly sought are methods that can, without sacrificing time, easily remove matrix interferences capable of inducing ionization suppression/enhancement
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