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Merck
CN

O0250000

Oxprenolol hydrochloride

European Pharmacopoeia (EP) Reference Standard

别名:

(RS)-1-(2-Allyloxyphenoxy)- 3-isopropylamino-2-propanol

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关于此项目

经验公式(希尔记法):
C15H23NO3 · HCl
化学文摘社编号:
分子量:
301.81
UNSPSC Code:
41116107
EC Number:
229-260-5
NACRES:
NA.24
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SMILES string

[Cl-].[N+H2](C(C)C)CC(O)COc1c(cccc1)OCC=C

InChI key

COAJXCLTPGGDAJ-UHFFFAOYSA-N

InChI

1S/C15H23NO3.ClH/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3;/h4-8,12-13,16-17H,1,9-11H2,2-3H3;1H

grade

pharmaceutical primary standard

API family

oxprenolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Oxprenolol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M A Martínez-Gómez et al.
Journal of pharmaceutical and biomedical analysis, 39(1-2), 76-81 (2005-06-02)
The intrinsic characteristics of capillary electrophoresis have made this technique a powerful tool in the chiral separation field. The present paper deals with the enantiomeric separation of oxprenolol enantiomers by affinity electrokinetic chromatography-partial filling technique using human serum albumin (HSA)
M Nogowska
Acta poloniae pharmaceutica, 57(5), 353-357 (2000-12-29)
Stability of series of O-acyl esters of oxprenolol prepared as potential pro-drugs, is investigated over the pH range 0.4-10 at 37 degrees C. Maximum stability of all esters occurred at pH 3-4. The most stable derivative was found to be
Erzsébet H Puhó et al.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 44(2), 194-202 (2007-03-03)
To evaluate the possible association between all kinds of drug treatments during pregnancy and isolated cleft lip with or without cleft palate (CL/P) and posterior cleft palate (PCP) in the offspring. The dataset of the large population-based Hungarian Case-Control Surveillance
K Görlitzer et al.
Die Pharmazie, 59(9), 678-682 (2004-10-23)
Alprenolol (1a) reacts with an excess of bromine to yield the tribromo derivative 3a by addition and monosubstitution, while applying oxprenolol (1b) the disubstituted tetrabromo derivative 2b is obtained. The N-dealkylated substance 3c was isolated as a by-product. Heating the
M Nogowska
Acta poloniae pharmaceutica, 57(4), 267-270 (2000-12-29)
The stability of each O-acyl derivative was investigated in a solution of hydrochloric acid, artificial gastric juice, phosphate buffer at pH 7.4 and in artificial intestinal juice. A study of the relationship between the structure and enzymatic hydrolysis of the

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