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Merck
CN

O0250000

Oxprenolol hydrochloride

European Pharmacopoeia (EP) Reference Standard

别名:

(RS)-1-(2-Allyloxyphenoxy)- 3-isopropylamino-2-propanol

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关于此项目

经验公式(希尔记法):
C15H23NO3 · HCl
化学文摘社编号:
分子量:
301.81
UNSPSC Code:
41116107
EC Number:
229-260-5
NACRES:
NA.24
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产品名称

Oxprenolol hydrochloride, European Pharmacopoeia (EP) Reference Standard

SMILES string

[Cl-].[N+H2](C(C)C)CC(O)COc1c(cccc1)OCC=C

InChI key

COAJXCLTPGGDAJ-UHFFFAOYSA-N

InChI

1S/C15H23NO3.ClH/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3;/h4-8,12-13,16-17H,1,9-11H2,2-3H3;1H

grade

pharmaceutical primary standard

API family

oxprenolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Oxprenolol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M I Maguregui et al.
Journal of chromatography. A, 949(1-2), 91-97 (2002-05-10)
A simple capillary zone electrophoretic method with UV detection has been developed for the quantitative determination of the beta-adrenoreceptor antagonists (beta-blockers) oxprenolol and timolol in human urine, preceded by a solid-phase extraction step. The electrophoretic separation was performed on a
S A B Salman et al.
Toxicology mechanisms and methods, 20(3), 137-142 (2010-02-05)
Many previous published methods for the quantitative determination of propranolol (PRN) in human plasma have poor recoveries and were not validated according to the FDA guideline. The aim of this study is to develop a simple HPLC method for detecting
P R Bontchev et al.
Journal of inorganic biochemistry, 83(1), 25-30 (2001-02-24)
The complexation between copper(II) and the antihypertensive drug oxprenolol (HOxp) was studied both in methanol and slightly alkaline aqueous media at Cu:HOxp molar ratio from 1:1 to 1:10. Copper(lI) forms two types of complexes-a mononuclear violet one, CuOxp2, with bidentately
Antonella De Rossi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 839(1-2), 6-11 (2005-12-21)
High sensitivity analysis of oxprenolol in spiked human urine has been performed by capillary zone electrophoresis (CZE) in ammonium formate buffer pH 2.5 using an uncoated capillary with 1cm length C18 on-capillary preconcentrator at the inlet side. The preconcentrator was
Ahmad Amini et al.
Electrophoresis, 29(19), 3952-3958 (2008-10-30)
This paper introduces four different modes of multiple-injection CZE (MICZE). The validity of these MICZE models was evaluated by the experimental data. Prior to the application of MICZE, the electrophoretic conditions are developed in the single-injection mode by adjusting different

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