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PHR1076

美托洛尔 (+)-酒石酸盐

Name: 美托洛尔 (+)-酒石酸盐
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)1-(异丙氨基)-3-[p-(β-甲氧基乙基)苯氧基] -2-丙醇 (+)-酒石酸盐, Lopressor

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关于此项目

线性分子式:

(C₁₅H₂₅NO₃)₂ · C₄H₆O₆

化学文摘社编号:

56392-17-7

分子量:

684.81

NACRES:

NA.24

PubChem Substance ID:

329823099

UNSPSC Code:

41116107

EC Number:

260-148-9

MDL number:

MFCD00056257

eCl@ss:

25140904

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属性

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. M1830000, traceable to USP 1441301

API family

metoprolol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

InChI key

YGULWPYYGQCFMP-CEAXSRTFSA-N

Gene Information

human ... ADRB1(153)

说明

General description

Metoprolol Tartrate is a β-blocking drug, showing antihypertensive and anti-ischemic effects. It is widely used in the treatment of hypertension and helps in controlling ventricular response in patients with atrial fibrillation.

Application

Metoprolol Tartrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using densitometric technique and spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA6905 in the slot below. This is an example certificate only and may not be the lot that you receive.

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象形图

GHS08,GHS09

警示词

Warning

危险代码

H361d,H411

预防性声明

P202 - P273 - P280 - P308 + P313 - P391 - P405

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

存储类别

11 - Combustible Solids

闪点 (F)

Not applicable

闪点 (°C)