跳转至内容
Merck
CN

PHR1076

美托洛尔 (+)-酒石酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)1-(异丙氨基)-3-[p-(β-甲氧基乙基)苯氧基] -2-丙醇 (+)-酒石酸盐, Lopressor

登录 查看组织和合同定价。

选择尺寸

关于此项目

线性分子式:
(C15H25NO3)2 · C4H6O6
化学文摘社编号:
56392-17-7
分子量:
684.81
NACRES:
NA.24
PubChem Substance ID:
329823099
UNSPSC Code:
41116107
EC Number:
260-148-9
MDL number:
MFCD00056257

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

InChI key

YGULWPYYGQCFMP-CEAXSRTFSA-N

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. M1830000, traceable to USP 1441301

API family

metoprolol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

Gene Information

human ... ADRB1(153)

正在寻找类似产品? 访问 产品对比指南

相关类别

General description

Metoprolol Tartrate is a β-blocking drug, showing antihypertensive and anti-ischemic effects. It is widely used in the treatment of hypertension and helps in controlling ventricular response in patients with atrial fibrillation.

Application

Metoprolol Tartrate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using densitometric technique and spectrophotometric technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6905 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

A validated HPLC method for estimation of metoprolol in human plasma
Aqil M, et al.
Acta Chromatographica , 19, 130-130 (2007)
Densitometric determination of metoprolol tartrate in pharmaceutical dosage forms
Vujic Z, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15(5), 581-585 (1997)
Current Cardiovascular Drugs, 15(4), 581-585 (2005)
AAS and spectrophotometric determination of propranolol HCl and metoprolol tartrate
El-Ries MA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 24(2), 179-187 (2000)
Thomas Kahan et al.
European journal of clinical investigation, 43(2), 141-151 (2013-01-03)
Although stable angina pectoris often carries a favourable prognosis, it remains important to identify patients with an increased risk of cardiovascular (CV) complications. Many new markers of disease activity and prognosis have been described. We evaluated whether common and easily
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持