PHR1119
D-樟脑
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
2-甘烷酮, 2-硼烷酮
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关于此项目
经验公式（希尔记法）:
C10H16O
化学文摘社编号:
分子量:
152.23
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
207-355-2
MDL number:
产品名称
D-樟脑, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
DSSYKIVIOFKYAU-XCBNKYQSSA-N
InChI
1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
SMILES string
CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. C0405000
traceable to USP 1087508
vapor density
5.24 (vs air)
vapor pressure
4 mmHg ( 70 °C)
API family
camphor
CofA
current certificate can be downloaded
autoignition temp.
870 °F
expl. lim.
3.5 %
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
178-182 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. D-Camphor is an acyclic terpenoid and one of the key volatile constituents of essential oils of plants Artemisia tridenta, Mentha longifolia ssp., Longifolia and some Lamiaceae species.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8982 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 2 Inhalation
target_organs
Lungs
存储类别
4.1B - Flammable solid hazardous materials
wgk
WGK 1
flash_point_f
147.2 °F - closed cup
flash_point_c
64 °C - closed cup
E Siegel et al.
Pediatric clinics of North America, 33(2), 375-379 (1986-04-01)
Camphor is present in several over-the-counter compounds of questionable use and therefore may be ingested by small children. Because seizures may follow ingestion of certain amounts, appropriate treatment is needed, including the use of anticonvulsants.
Jeffrey N Love et al.
The Journal of emergency medicine, 27(1), 49-54 (2004-06-29)
Serious pediatric toxicity resulting from exposure to small amounts of camphor-containing products has long been a problem. Twenty years ago the United States Food and Drug Administration took several actions in an attempt to ameliorate this risk. Despite these changes
Gustav Georg Belz et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 10 Suppl 4, 61-67 (2003-06-17)
Independent, double-blinded, randomized, placebo-controlled studies using sublingual/oral administration of D-camphor, an extract from fresh crataegus berries, and a combination of the two (CCC) yielded the following results: Both the D-camphor and the extract from fresh crataegus berries, the components of
Camphor: a chiral starting material in natural product synthesis.
T Money
Natural product reports, 2(3), 253-289 (1985-06-01)
Weiyang Chen et al.
Molecules (Basel, Switzerland), 18(5), 5434-5454 (2013-05-15)
The fragrant camphor tree (Cinnamomum camphora) and its products, such as camphor oil, have been coveted since ancient times. Having a rich history of traditional use, it was particularly used as a fumigant during the era of the Black Death
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