PHR1155
2-辛基-1-十二烷醇
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
2-辛基-1-十二烷醇
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关于此项目
线性分子式:
CH3(CH2)9CH[(CH2)7CH3]CH2OH
化学文摘社编号:
分子量:
298.55
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
226-242-9
MDL number:
产品名称
2-辛基-1-十二烷醇, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
LEACJMVNYZDSKR-UHFFFAOYSA-N
InChI
1S/C20H42O/c1-3-5-7-9-11-12-14-16-18-20(19-21)17-15-13-10-8-6-4-2/h20-21H,3-19H2,1-2H3
SMILES string
CCCCCCCCCCC(CO)CCCCCCCC
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. O0101000
traceable to USP 1477808
API family
octyldodecanol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.453 (lit.)
bp
234-238 °C/33 mmHg (lit.)
mp
−1-1 °C (lit.)
density
0.838 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Application
Octyldodecanol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7139 in the slot below. This is an example certificate only and may not be the lot that you receive.
Values of analytes vary lot to lot.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
370.4 °F - open cup
flash_point_c
188 °C - open cup
Selection of solubility parameters for characterization of pharmaceutical excipients
Adamska K, et al.
Journal of Chromatography A, 1171(1-2), 90-97 (2007)
Solvent effect on photostability of butyl methoxy di benzoyl methane formulated in solution and emulsion
DURANGO S, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(9), 181-186 (2015)
Bethânia Andrade de Vargas et al.
Journal of biomedical nanotechnology, 8(2), 330-336 (2012-04-21)
This article describes the development of topical hydrogels containing genistein-loaded nanoemulsions, obtained by means of spontaneous emulsification. This procedure yielded monodisperse nanoemulsions in a sub 250 nm range exhibiting negative zeta-potential and low viscosity. The formulations were incorporated into acrylic-acid
Thomas Mensing et al.
AIHA journal : a journal for the science of occupational and environmental health and safety, 64(4), 461-466 (2003-08-12)
Cooling lubricants are used in the metal industry during drilling or turning. Vapors and aerosols of these lubricants are suspected to induce airway hyperresponsiveness (AHR) in exposed workers. In a previous study the authors demonstrated that water-soluble lubricants induce AHR
Genital swelling caused by octyldodecanol contact dermatitis.
G Dawn et al.
Clinical and experimental dermatology, 28(2), 228-229 (2003-03-26)
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