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线性分子式:
CH3CH=CHC6H4OCH3
化学文摘社编号:
分子量:
148.20
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
224-052-0
Beilstein/REAXYS Number:
774229
MDL number:
产品名称
反式茴香脑, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
InChI key
RUVINXPYWBROJD-ONEGZZNKSA-N
SMILES string
COc1ccc(\C=C\C)cc1
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1035005
API family
anethole
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.561 (lit.)
bp
234-237 °C (lit.)
mp
20-21 °C (lit.)
density
0.988 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Biochem/physiol Actions
天然存在的苯丙烯衍生物,低浓度时具有雌激素的特征,高浓度时对癌细胞系具有细胞毒性。该细胞毒性与反式茴香脑代谢为 4-羟基-1-丙烯基苯有关。
Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Application
trans-Anethole may be used as an analytical reference standard for the determination of the analyte in raw material, food products and pharmaceutical formulations by high performance liquid chromatography and gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
trans-Anethole is an aromatic monoterpenoid compound and derivative of phenylpropene. It is predominantly used as a fragrance in cosmetics and as a flavoring agent in food and pharmaceutical industries.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Other Notes
This compound is commonly found in plants of the genus: pimpinella
To see an example of a Certificate of Analysis for this material enter LRAC3326 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
213.8 °F
flash_point_c
101 °C
Anethole
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 40(1)(3-4), 5576-5576 (2018)
Fast quantitative determination of volatile constituents in fennel by headspace-gas chromatography
Krizman M, et al.
Analytica Chimica Acta, 557(1-2), 267-271 (2006)
Identification by HPLC- DAD and HPLC- MS analyses and quantification of constituents of fennel teas and decoctions
Bilia AR, et al.
Journal of Agricultural and Food Chemistry, 48(10), 4734-4738 (2000)
LC determination of anethole in aniseed drinks
Jurado JM, et al.
Chromatographia, 64(3-4), 223-226 (2006)
Determination of trans-anethole in Salvia sclarea essential oil by liquid chromatography and GC-MS
Fiori J, et al
Journal of Separation Science, 25(10-11), 703-709 (2002)
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