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Merck
CN

PHR1235

视黄醇(维生素A)棕榈酸酯 CRM

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

维生素A棕榈酸酯, 全−反式−视黄醇棕榈酸酯, 维生素 A 棕榈酸酯

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关于此项目

经验公式（希尔记法）:
C36H60O2
化学文摘社编号:
79-81-2
分子量:
524.86
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823240
EC Number:
201-228-5
Beilstein/REAXYS Number:
1917366
MDL number:
MFCD00019414

主要文件

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产品名称

视黄醇(维生素A)棕榈酸酯 CRM, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1602502

API family

retinyl compounds

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

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相关类别

Application

棕榈酸视黄酯可用作药物参考标准品，通过色谱和分光光度技术对药物制剂中的分析物进行测定。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Biochem/physiol Actions

评论：维生素 A 代谢。

General description

用于质量控制的制药二级认证标准品，为制药实验室和制造商内部工作标准品提供了一种方便、高性价比的替代方案。视黄醇棕榈酸酯属于一类名为类视黄醇的化合物，化学性质类似于维生素 A。它对视力、皮肤和免疫功能具有有益作用，可抑制细胞增殖并预防癌症。它是重要的膳食和治疗性化合物。

Other Notes

要查看此材料的分析证书样本，请在下框中输入LRAB3694。这只是一个示例证书，可能与您收到的批次不符。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

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Vitamin A Palmitate-β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties
Vilanova N and Solans C
Food Chemistry, 175(1-2), 529 -5535 (2015)
Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography -atmospheric pressure chemical ionization -mass spectrometry
van Breemen RB, et al.
Journal of Chromatography A, 794(1-2), 245-251 (1998)
S Pedersen-Bjergaard et al.
Journal of chromatography. A, 876(1-2), 201-211 (2000-05-24)
Microemulsion electrokinetic chromatography (MEEKC) was carried out in a pH 2.5 phosphate buffer to effectively suppress the electroosmotic flow (EOF). With 66.6% (w/w) 25 mM phosphate buffer pH 2.5, 20.0% (w/w) 2-propanol, 6.6% (w/w) 1-butanol, 6.0% (w/w) sodium lauryl sulphate
M B Lindström et al.
Biochimica et biophysica acta, 959(2), 178-184 (1988-03-25)
The pancreatic enzyme carboxyl ester lipase (CEL) has been shown to hydrolyse a large number of different esters, including triacylglycerols, cholesteryl esters and retinyl esters with an absolute requirement for bile salts. Some of the lipids that are substrates for
Machteld Van Lieshout et al.
Journal of agricultural and food chemistry, 51(17), 5123-5130 (2003-08-09)
Previously, we have presented a method for quantifying beta-carotene bioavailability based on analysis in serum, following administration of (13)C-labeled beta-carotene. Because stool samples can be collected noninvasively, we have now extended the method to measure the bioavailability based on measurements
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