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PHR1236

视黄醇乙酸酯

Name: 视黄醇乙酸酯
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

视黄醇乙酸酯, 维生素 A 醋酸酯, 醋酸维生素 A

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关于此项目

经验公式（希尔记法）:

C₂₂H₃₂O₂

化学文摘社编号:

127-47-9

分子量:

328.49

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823241

EC Number:

204-844-2

Beilstein/REAXYS Number:

1915439

MDL number:

MFCD00019413

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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. R0300000, traceable to USP 1716002

API family

retinyl compounds

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

57-58 °C

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

General description

用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
视黄醇乙酸酯属于类视黄醇的化合物，其与维生素A化学结构相关。类视黄醇可通过口服和局部给药的方式用于痤疮和牛皮癣的治疗。

Application

这些二级标准品是合格的有证标准物质。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

在我们的NMR在线平台ChemisTwin®上可以找到本品对应的数字化标准物质。您可使用ChemisTwin®上的数字等效品鉴定您的样品并进行定量分析（使用数字化外标）。可查看该物质的NMR谱图，只需点击几次鼠标，就能进行在线样品比对。欢迎点击了解更多，开启免费试用之旅。

要查看该材料的分析证书示例，请在下面的栏位中输入 LRAB3672 。这只是一个示例证书，可能不是您收到的批次。

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

pictograms

GHS08

signalword

Danger

hcodes

H360D,H413

pcodes

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

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Inhibition of rat mammary carcinogenesis by short dietary exposure to retinyl acetate

McCormick DL, et al.

Cancer research, 40(4), 1140-1143 (1980)

Inhibitory Effects of Retinoic Acid or Retinyl Acetate on the Growth of Untransformed, Transformed, and Tumor Cells In Vitro

Lotan R and Nicolson GL

Journal of the National Cancer Institute, 59(6), 1717-1722 (1977)

Vademecum for Vitamin Formulations (2001)

A randomized controlled trial to assess the impact of dietary energy sources, feed supplements, and the presence of super-shedders on the detection of Escherichia coli O157:H7 in feedlot cattle using different diagnostic procedures.

Natalia Cernicchiaro et al.

Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)

Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's

Involvement of all-trans-retinal in acute light-induced retinopathy of mice.

Akiko Maeda et al.

The Journal of biological chemistry, 284(22), 15173-15183 (2009-03-24)

Exposure to bright light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental animals, but the mechanism(s) remain unclear. We investigated whether the retinoid cycle (i.e. the series of biochemical reactions required for vision through continuous generation

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实验方案

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

全球贸易项目编号

货号	GTIN
PHR1236-1G	04061837884061

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