PHR1259
噻菌灵
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
噻菌灵, 2-(4-噻唑基)苯并咪唑
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关于此项目
经验公式（希尔记法）:
C10H7N3S
化学文摘社编号:
分子量:
201.25
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-725-8
Beilstein/REAXYS Number:
611403
MDL number:
产品名称
噻菌灵, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
WJCNZQLZVWNLKY-UHFFFAOYSA-N
InChI
1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
SMILES string
c1ccc2[nH]c(nc2c1)-c3cscn3
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. T1410000
traceable to USP 1655000
API family
thiabendazole
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Thiabendazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and preparations by spectrophotometric, spectrofluorimetric and chromatography techniques.
General description
Thiabendazole is an orally effective broad spectrum anthelmintic and antimycotic drug with limited side-effects.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9062 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
农药列管产品
此项目有
Determination of 81 pharmaceutical drugs by high performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole--linear ion trap in different types of water in Serbia
Petrovic M, et al.
The Science of the Total Environment, 468(2), 415-428 (2014)
Development of a spectrofluorimetric method for determination of thiabendazole in tablets
Kucukkolbasi S and Kilic E
Journal of Applied Pharmaceutical Science, 3(2), 19-19 (2013)
Mechanism of action of the fungicide thiabendazole, 2-(4?-thiazolyl) benzimidazole
Allen PM and Gottlieb D
Applied and Environmental Microbiology, 20(6), 919-926 (1970)
Studies on the toxicologic and pharmacologic properties of thiabendazole
Robinson HJ, et al.
Toxicology and Applied Pharmacology, 7(1), 53-63 (1965)
Suely R C Andrade et al.
Journal of pharmaceutical and biomedical analysis, 33(4), 655-665 (2003-11-19)
Three multivariate calibration methods, Principal Component Regression (PCR), the K-matrix method and Q-mode factor analysis followed by varimax and Imbrie's oblique rotations were applied to the simultaneous spectrophotometric determinations of mebendazole (MBZ)-cambendazole (CBZ) and thiabendazole (TBZ)-mebendazole in commercial samples of
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