PHR1280
木糖醇
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
1,2,3,4,5-戊五醇
等级
certified reference material
pharmaceutical secondary standard
质量水平
Agency
traceable to Ph. Eur. X0080000
traceable to USP 1720600
API类
xylitol
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
94-97 °C (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-30°C
SMILES字符串
OC[C@@H](O)[C@H](O)[C@@H](O)CO
InChI
1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+
InChI key
HEBKCHPVOIAQTA-SCDXWVJYSA-N
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一般描述
用于 质量控制的认证药物二级标准品为 制药实验室和制造商提供了一种方便且具有成本效益 的主要标准替代品木糖醇是一种天然存在的多元糖醇，具有很高的甜味和防龋性能。
应用
木糖醇可用作药物标准品，用于通过毛细管等速电泳测定药物制剂中的分析物。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
分析说明
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
其他说明
想要查看本品的检验报告示例，请在下框中输入LRAC4431。这只是一个示例证书，可能与您收到的批次不符。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Separation and determination of sorbitol and xylitol in multi-component pharmaceutical formulations by capillary isotachophoresis
Pospisilova M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 17(3), 387-392 (1998)
The effect of xylitol on dental caries and oral flora
Nayak PA, et al.
Clinical, cosmetic and investigational dentistry, 6, 89-89 (2014)
M C Ammons et al.
Biofouling, 29(4), 443-455 (2013-04-12)
Medically relevant biofilms have gained a significant level of interest, in part because of the epidemic rise in obesity and an aging population in the developed world. The associated comorbidities of chronic wounds such as pressure ulcers, venous leg ulcers
Mette K Keller et al.
BMC oral health, 12, 44-44 (2012-10-25)
The increasing interest in probiotic lactobacilli in health maintenance has raised the question of potential risks. One possible side effect could be an increased acidogenicity in dental plaque. The aim of this study was to investigate the effect of probiotic
A V Ritter et al.
Journal of dental research, 92(6), 512-517 (2013-04-17)
The Xylitol for Adult Caries Trial was a three-year, double-blind, multi-center, randomized clinical trial that evaluated the effectiveness of xylitol vs. placebo lozenges in the prevention of dental caries in caries-active adults. The purpose of this secondary analysis was to
实验方案
Separation of Maltotriose; Maltose; Xylitol
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