PHR1326
碳酸钙
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
碳酸钙
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关于此项目
线性分子式:
CaCO3
化学文摘社编号:
分子量:
100.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-439-9
Beilstein/REAXYS Number:
8008338
MDL number:
产品名称
碳酸钙, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
VTYYLEPIZMXCLO-UHFFFAOYSA-L
InChI
1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
SMILES string
[Ca++].[O-]C([O-])=O
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1086403
API family
calcium carbonate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
density
2.93 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
Quality Level
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Application
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
General description
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。碳酸钙是一种广泛存在于自然界中的物质，通常被称为方解石。碳酸钙用于制造纸张、油漆、玻璃和陶瓷、聚合物的复合、环境应用（例如废水处理）以及作为涂料和涂料的增量剂。
Other Notes
想要查看本品的检验报告示例，请在下框中输入LRAC3446。这只是一个示例证书，可能与您收到的批次不符。
该认证标准物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在检验报告上找到。
Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
存储类别
13 - Non Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Calcium carbonate urolithiasis in an adult male cynomolgus monkey.
C M O'Rourke et al.
Laboratory animal science, 45(2), 222-224 (1995-04-01)
Julyan H E Cartwright et al.
Angewandte Chemie (International ed. in English), 51(48), 11960-11970 (2012-11-06)
Although the polymorphism of calcium carbonate is well known, and its polymorphs--calcite, aragonite, and vaterite--have been highly studied in the context of biomineralization, polyamorphism is a much more recently discovered phenomenon, and the existence of more than one amorphous phase
Dongni Ren et al.
Micron (Oxford, England : 1993), 42(3), 228-245 (2010-10-19)
The review focuses on the effects of several important additives and templates controlling the calcium carbonate crystals formation and the complexity of the crystal morphologies in vitro. Additives include soluble matrices extracted from shells and pearls, amino-acids, magnesium ions and
Polysaccharides and proteoglycans in calcium carbonate-based biomineralization.
José L Arias et al.
Chemical reviews, 108(11), 4475-4482 (2008-07-26)
Claudia Gagnon et al.
PloS one, 9(10), e109607-e109607 (2014-10-10)
To examine whether combined vitamin D and calcium supplementation improves insulin sensitivity, insulin secretion, β-cell function, inflammation and metabolic markers. 6-month randomized, placebo-controlled trial. Ninety-five adults with serum 25-hydroxyvitamin D [25(OH)D] ≤55 nmol/L at risk of type 2 diabetes (with
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