PHR1467
异丙嗪
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
异丙嗪 盐酸盐, 10-(2-二甲基氨基-1-丙基)吩噻嗪 盐酸盐
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关于此项目
经验公式（希尔记法）:
C17H20N2S · HCl
化学文摘社编号:
分子量:
320.88
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-375-2
Beilstein/REAXYS Number:
4166397
MDL number:
Quality Segment
grade
certified reference material, pharmaceutical secondary standard
agency
USP 1570009, traceable to Ph. Eur. P3400000
API family
promethazine
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI
1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI key
XXPDBLUZJRXNNZ-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
Promethazine hydrochloride belongs to the group of phenothiazine derivatives. It is commonly used as an antihistaminic for most prominently enhancing the anesthetic, sedative and analgesic effect of other drugs. It also shows antipyretic and antiemetic properties, when used in combination with paracetamol. It is also used to provide symptomatic relief of hypersensitivity reactions.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Promethazine hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectroanalytical technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3015 in the slot below. This is an example certificate only and may not be the lot that you receive.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable