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PHR1470

东莨菪碱氢溴酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

东莨菪碱 氢溴酸盐

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关于此项目

经验公式（希尔记法）:
C17H21NO4 · HBr · 3H2O
化学文摘社编号:
6533-68-2
分子量:
438.31
UNSPSC Code:
41116107
PubChem Substance ID:
329823400
NACRES:
NA.24
MDL number:
MFCD00012647
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. H1500000, traceable to USP 1610001

API family

scopolamine, hyoscine

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Br.N1([C@@H]2[C@@H]3O[C@@H]3[C@H]1C[C@H](C2)OC(=O)[C@H](CO)c4ccccc4)C

InChI

1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

InChI key

WTGQALLALWYDJH-MOUKNHLCSA-N

Gene Information

human ... CHRM1(1128)

General description

Scopolamine Hydrobromide is the hydrobromide salt of scopolamine, naturally found in belladonna plant. It belongs to the group of cycloplegic drugs, which produces cycloplegia. Its mode of action involves inhibiting the action of acetylcholine at muscarinic receptors in the ciliary muscle.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards

Application

Scopolamine Hydrobromide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7821 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Dictionary of Optometry and Visual Science, 590(2), 341-353 (2014)
LC determination of atropine sulfate and scopolamine hydrobromide in pharmaceuticals.
Ceyhan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 399-406 (2001)
Topical Drug Bioavailability, Bioequivalence, and Penetration, 590(2), 341-353 (1993)
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全球贸易项目编号

货号GTIN
PHR1470-500MG04061834416937