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Merck
CN

PHR1493

Supelco

盐酸毛果芸香碱

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

毛果芸香碱 盐酸盐, (3S,4R)-4,5-二氢-3-乙基-4-(1-甲基-1H-咪唑-5-基甲基)-2(3H)-呋喃酮 盐酸盐

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关于此项目

经验公式（希尔记法）:
C11H16N2O2 · HCl
CAS Number:
54-71-7
分子量:
244.72
Beilstein:
4034491
EC 号:
200-212-5
MDL编号:
MFCD00012722
UNSPSC代码:
41116107
PubChem化学物质编号:
329823415
NACRES:
NA.24

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. P1650000
traceable to USP 1538902

API类

pilocarpine

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

202-205 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

Cl.CC[C@H]1[C@H](COC1=O)Cc2cncn2C

InChI

1S/C11H16N2O2.ClH/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;/h5,7-8,10H,3-4,6H2,1-2H3;1H/t8-,10-;/m0./s1

InChI key

RNAICSBVACLLGM-GNAZCLTHSA-N

基因信息

human ... CHRM1(1128), CHRM3(1131)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Pilocarpine Hydrochloride may be used as a pharmaceutical reference standard for the determination of pilocarpine in opthalmic dispersions and serum samples by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

非选择性毒蕈碱型乙酰胆碱受体激动剂；用于诱导癫痫实验模型。

分析说明

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3041 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H300 + H330

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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访问文档库

Simple chemiluminescence determination of pilocarpine in pharmaceuticals and human serum.
Keyvanfard M, et al.
Acta Chimica Slovenica, 58(3), 379-382 (2011)
Determination of pilocarpine by HPLC in presence of isopilocarpine a pH-sensitive polymer in ophthalmic dispersions
Ibrahim H, et al.
Journal of Pharmaceutical and Biomedical Analysis, 5(4), 379-382 (1987)

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