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Merck
CN

PHR1512

麦角甾醇

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

麦角甾醇, (3β)-麦角-5,7,22-三烯甘油-3-醇, 3β-羟基-5,7,22-麦角三烯, 维生素原 D2

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关于此项目

经验公式（希尔记法）:
C28H44O
化学文摘社编号:
57-87-4
分子量:
396.65
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823430
EC Number:
200-352-7
Beilstein/REAXYS Number:
2338604
MDL number:
MFCD00003623

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产品名称

麦角甾醇, Pharmaceutical Secondary Standard; Certified Reference Material

InChI

1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1

InChI key

DNVPQKQSNYMLRS-APGDWVJJSA-N

SMILES string

[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. E1100000
traceable to USP 1241007

API family

ergosterol

form

solid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

156-158 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

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Analysis Note

这些二级标准品可追溯至USP、EP和BP一级标准品。

Application

这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

General description

麦角固醇是存在于真菌和某些原生生物（如锥虫）细胞膜中的维生素D2的生物前体。它是真菌细胞膜中的主要固醇。
用于质量控制的药物二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Other Notes

如需查看本品的分析证书示例，请在下框中输入 LRAA3319。这只是一个示例证书并可能不是您所收到的批次。
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

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Oleaginous yeasts are considered as a potential lipid source for food, feed and biofuel production. In order to make the yeast-based lipid production environmentally and economically sustainable, there is a need for screening studies in order to find the best
Analysis of ergosterol in single kernel and ground grain by gas chromatography- mass spectrometry
Dong Y, et al.
Journal of Agricultural and Food Chemistry, 54(12), 4121-4125 (2006)
Leo T Mpofu et al.
Planta, 240(2), 239-250 (2014-05-13)
A lack of understanding of host-by-pathogen relations can hinder the success of breeding for resistance to a major disease. Fungal strain pathogenicity has to be understood from the virulence it can cause on susceptible genotypes and host resistance indicates which
Benoît Pilmis et al.
The Journal of antimicrobial chemotherapy, 70(1), 14-22 (2014-09-11)
Antifungal prescription remains a challenge in pregnant women because of uncertainties regarding fetal toxicity and altered maternal pharmacokinetic parameters that may affect efficacy or increase maternal and fetal toxicity. We present updated data reviewing the available knowledge and current recommendations
Wei-Jie Wu et al.
PloS one, 9(4), e95359-e95359 (2014-04-17)
Response surface methodology (RSM) was used to determine the optimum vitamin D2 synthesis conditions in oyster mushrooms (Pleurotus ostreatus). Ultraviolet B (UV-B) was selected as the most efficient irradiation source for the preliminary experiment, in addition to the levels of
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