跳转至内容
Merck
CN

PHR1524

坦洛新

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

盐酸坦洛新 盐酸盐

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C20H28N2O5S · HCl
化学文摘社编号:
106463-17-6
分子量:
444.97
NACRES:
NA.24
PubChem Substance ID:
329823437
UNSPSC Code:
41116107
MDL number:
MFCD00922997

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

坦洛新, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

ZZIZZTHXZRDOFM-XFULWGLBSA-N

SMILES string

Cl.CCOc1ccccc1OCCN[C@H](C)Cc2ccc(OC)c(c2)S(N)(=O)=O

InChI

1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000650
traceable to USP 1643260

API family

tamsulosin

CofA

current certificate can be downloaded

packaging

ampule of 1 × 200 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

Quality Level

300

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

正在寻找类似产品? 访问 产品对比指南

相关类别

Biochem/physiol Actions

Tamsulosin is an α1A/1D-adrenoceptor antagonist used as a treatment of benign prostatic hypertrophy (BPH). Its activity as an ? blocker also affects the iris, and has led to complications during cataract surgery, a condition called "floppy iris" syndrome.
Tamsulosin is a α1A/1D-adrenoceptor antagonist; Used as a treatment of BPH (benign prostatic hypertrophy).

Application

Tamsulosin hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Tamsulosin hydrochloride is a subtypeselective a1A and a1D adrenoceptor antagonist, which exists in two enantiomeric forms, of which the R-isomer is the pharmaceutically active component. It is used to reduce urinary obstruction and is also involved in relieving the symptoms associated with symptomatic benign prostatic hyperplasia.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC0288 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Validated stability indicating HPTLC method for the determination of Tamsulosin hydrochloride in pharmaceutical dosage forms
Choudhari.PV and Nikalje GPA
International Journal of ChemTech Research, 2(1), 646-652 (2010)
Development and validation of stability-indicating HPTLC determination of tamsulosin in bulk and pharmaceutical dosage form
Bari.BS, et al.
Chromatography Research International, 2011(2), 197-205 (2011)
Validated RP-HPLC and TLC methods for simultaneous estimation of tamsulosin hydrochloride and finasteride in combined dosage forms
Patel B.D and Patel J.N
Acta pharmaceutica, 60(2), 197-205 (2010)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持