PHR1601
伐昔洛韦
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
伐昔洛韦 盐酸盐
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经验公式（希尔记法）:
C13H20N6O4 · HCl
化学文摘社编号:
分子量:
360.80
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
eCl@ss:
25140904
Quality Segment
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0000834, traceable to USP 1707839
API family
valacyclovir
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical
pharmaceutical
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2C(=O)NC(N)=Nc12
InChI
1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1
InChI key
ZCDDBUOENGJMLV-QRPNPIFTSA-N
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Valacyclovir HCl is the hydrochloride salt of L-valyl ester, a prodrug of the antiviral drug acyclovir. Its mode of action involves the inhibition of the viral DNA polymerase and the termination of the viral DNA chain.It is widely used against herpes zoster, herpes simplex and herpes B.
Valacyclovir HCl is the hydrochloride salt of L-valyl ester, a prodrug of the antiviral drug acyclovir. Its mode of action involves the inhibition of the viral DNA polymerase and the termination of the viral DNA chain.It is widely used against herpes zoster, herpes simplex and herpes B.
Valacyclovir is a prodrug of acyclovir. It is an L-valyl ester and works against herpes simplex virus type and varicella zoster virus.
Application
It was used as reference standard for the quantification of valayclovir and its metabolite, from human plasma using LC/ESI-MS method.
Valacyclovir HCl may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3707 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
警示词
Warning
危险代码
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable