跳转至内容
Merck
CN

PHR1611

巯嘌呤

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

6-巯基嘌呤 一水合物, 6-嘌呤硫醇, 6-硫代嘌呤

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C5H4N4S·H2O
化学文摘社编号:
6112-76-1
分子量:
170.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823508
EC Number:
200-037-4
Beilstein/REAXYS Number:
4012091
MDL number:
MFCD03854445

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

巯嘌呤, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

WFFQYWAAEWLHJC-UHFFFAOYSA-N

InChI

1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2

SMILES string

O.S=C1NC=Nc2nc[nH]c12

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1392002

API family

mercaptopurine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

Gene Information

human ... PPAT(5471)

正在寻找类似产品? 访问 产品对比指南

相关类别

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Mercaptopurine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, suspensions, and double drug liposomes by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mercaptopurine is an anticancer and an immunosuppressive drug employed for the management of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn′s disease, etc. Its mode of action involves interference in the nucleic acid synthesis by the inhibition of purine metabolism.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3476 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Muta. 2 - Repr. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR DETERMINATION OF MERCAPTOPURINE-AN ANTI CANCER DRUG IN PHARMACEUTICAL FORMULATIONS
Suman P, et al.
European Journal of Biomedical AND Pharmaceutical sciences, 5(5), 752-759 (2018)
Effect of buffer and antioxidant on stability of a mercaptopurine suspension
Aliabadi HM, et al.
American Journal of Health-System Pharmacy, 65(5), 441-447 (2008)
6-mercaptopurine and daunorubicin double drug liposomes?preparation, drug-drug interaction and characterization
Agrawal V, et al.
Journal of liposome research, 15(3-4), 141-155 (2005)
Mepivacaine hydrochloride
USP42-NF37
United States Pharmacopeia/National Formulary, 40(5), 2750-2750 (2019)

相关内容

最新推出的满足海关审查要求的标准物质

默克Supelco®标准物质不断推出或更新满足海关及法规要求的标准物质。每年我们约有上百种的新CRM或标准物质上市，在此我们尽可能多的列出满足海关及法规要求的标准物质。

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持