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Merck
CN

PHR1627

维库溴铵

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

维库溴铵

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关于此项目

经验公式（希尔记法）:
C34H57BrN2O4
化学文摘社编号:
50700-72-6
分子量:
637.73
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823518
EC Number:
256-723-9
Beilstein/REAXYS Number:
4837308
MDL number:
MFCD00867762

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产品名称

维库溴铵, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

VEPSYABRBFXYIB-PWXDFCLTSA-M

InChI

1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1

SMILES string

[Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@@H]([C@@H]4OC(C)=O)[N+]5(C)CCCCC5)[C@@]2(C)C[C@@H]1N6CCCCC6

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000561
traceable to USP 1711155

API family

vecuronium

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Vecuronium Bromide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography and capillary zone elctrophoresis techniques.

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Vecuronium Bromide is a nondepolarizing neuromuscular blocking agent, which helps for adequate muscle relaxation for all types of surgical procedures in the absence of cardiorespiratory depressant effects of deep anesthesia.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA5296 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

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Determination of vecuronium bromide in pharmaceuticals: Development, validation and comparative study of HPLC and CZE analytical methods
Garcia LP, et al.
Chromatographia, 73(7), 799-805 (2011)

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