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文件

PHR1640

Supelco

氢溴酸西酞普兰

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
氢溴酸西酞普兰 氢溴酸盐, 1-[3-（二甲氨基）丙基]-1-（4-氟苯基）-1,3-二氢-5-异苯并呋喃甲腈 氢溴酸盐
经验公式（希尔记法）:
C20H21FN2O · HBr
CAS号:
59729-32-7
分子量:
405.30
EC 号:
261-890-6
MDL编号:
MFCD02101306
PubChem化学物质编号:
329823528
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 1153
traceable to Ph. Eur. Y0001008
traceable to USP 1134233

API family

citalopram

CofA

current certificate can be downloaded

包装

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

Br[H].CN(C)CCCC1(OCc2cc(ccc12)C#N)c3ccc(F)cc3

InChI

1S/C20H21FN2O.BrH/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H

InChI key

WIHMBLDNRMIGDW-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

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相关类别

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Citalopram Hydrobromide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

有效的选择性 5-羟色胺摄取抑制剂 (Ki = 5.4 nM)；抗抑郁药

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB7789 in the slot below. This is an example certificate only and may not be the lot that you receive.

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相关产品

产品编号
说明
价格

1134233

氢溴酸西酞普兰 氢溴酸盐, United States Pharmacopeia (USP) Reference Standard

1134244

Citalopram Related Compound A, United States Pharmacopeia (USP) Reference Standard

1134222

Citalopram Related Compound H, United States Pharmacopeia (USP) Reference Standard

1134197

Citalopram Related Compound G, United States Pharmacopeia (USP) Reference Standard

1134288

Citalopram Related Compound E, United States Pharmacopeia (USP) Reference Standard

1134266

Citalopram Related Compound C, United States Pharmacopeia (USP) Reference Standard

1134255

Citalopram Related Compound B, United States Pharmacopeia (USP) Reference Standard

1134277

Citalopram Related Compound D, United States Pharmacopeia (USP) Reference Standard

1134299

Citalopram Related Compound F, United States Pharmacopeia (USP) Reference Standard

Y0000855

西酞普兰, European Pharmacopoeia (EP) Reference Standard

Y0001008

氢溴酸西酞普兰 氢溴酸盐, European Pharmacopoeia (EP) Reference Standard

Y0001007

氢溴酸西酞普兰 盐酸盐, European Pharmacopoeia (EP) Reference Standard

1134142

R-Citalopram oxalate, United States Pharmacopeia (USP) Reference Standard

PHR1906

西酞普兰相关化合物H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1863

西酞普兰相关化合物F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1902

西酞普兰相关化合物C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1904

西酞普兰相关化合物E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1903

西酞普兰相关化合物D, Pharmaceutical Secondary Standard; Certified Reference Material

BP1153

氢溴酸西酞普兰 氢溴酸盐, British Pharmacopoeia (BP) Reference Standard

PHR1905

西酞普兰相关化合物B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1901

西酞普兰相关化合物A, Pharmaceutical Secondary Standard; Certified Reference Material

BP1154

西酞普兰杂质标准品, British Pharmacopoeia (BP) Reference Standard

象形图

Exclamation markHealth hazard
GHS07,GHS08

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - STOT SE 3

靶器官

Central nervous system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Quantitative determination of citalopram hydrobromide by spectro- photometry and chemometry in presence of its degradation products and additives in pharmaceutical preparation.
Amer SM, et al.
Analytical Chemistry, 16(2), 53-62 (2016)
Spectrophotometric Determination of Citalopram Hydrobromide in Pharmaceuticals.
Narayana B and Veena K
Journal of the Mexican Chemical Society, 54(2), 98-102 (2010)
Development and Application of Spectrophotometric Methods for the Determination of Citalopram Hydrobromide in Dosage Forms.
Raza A
Chemical & Pharmaceutical Bulletin, 54(4), 432-434 (2006)
Afzal Misrani et al.
Brain research bulletin, 155, 11-18 (2019-11-20)
Curtailment of sleep in modern society leads to a spectrum of neuropsychiatric disorders. However, the molecular mechanisms underlying the effects of sleep deprivation (SD) remain elusive and currently there is no effective therapy to alleviate these effects. Here, we aimed

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