所有图片(1)

文件

PHR1656

盐酸西替利嗪

Name: 盐酸西替利嗪
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

登录查看公司和协议定价

所有图片(1)

别名:

西替利嗪二盐酸盐, Virlix, Zyrtec^®, [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid 二盐酸盐

经验公式（希尔记法）:

C₂₁H₂₅ClN₂O₃ · 2HCl

CAS号:

83881-52-1

分子量:

461.81

MDL编号:

MFCD00941428

PubChem化学物质编号:

329823534

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 837
traceable to Ph. Eur. C0980650
traceable to USP 1102929

API类

cetirizine

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

OC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl

InChI

1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H

InChI key

PGLIUCLTXOYQMV-UHFFFAOYSA-N

基因信息

human ... HRH1(3269)

正在寻找类似产品? Visit 产品对比指南

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cetirizine hydrochloride, a second generation antihistaminic drug, is one of the carboxylated metabolites of hydroxyzine that can typically bind to histamine H₁ receptor. It is effective against diseases such as urticaria, angioedema, allergies and hay fever.

应用

Cetirizine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA5757 in the slot below. This is an example certificate only and may not be the lot that you receive.

1102930

1112467

4-氯二苯甲酮, United States Pharmacopeia (USP) Reference Standard

1102952

1102941

PHR1710

1102963

BP837

西替利嗪盐酸盐, British Pharmacopoeia (BP) Reference Standard

BP1081

西替利嗪杂质标准品, British Pharmacopoeia (BP) Reference Standard

BP441

1,4-Bis(4-chlorobenzhydryl)piperazine, British Pharmacopoeia (BP) Reference Standard

PHR2620

4-氯二苯甲酮, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2852

PHR3195

左西替利嗪二盐酸盐, pharmaceutical secondary standard, certified reference material

象形图

GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

输入产品批号来搜索分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

为方便起见，与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码？

如何查找产品货号

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题？欢迎随时联系我们技术服务寻求帮助

如何查找COA批号

批号可以在产品标签上"批“ （Lot或Batch）字后面找到。

Aldrich 产品

如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。
如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

A rapid, stability indicating RP-UPLC method for simultaneous determination of ambroxol hydrochloride, cetirizine hydrochloride and antimicrobial preservatives in liquid pharmaceutical formulation.

Trivedi RK, et al.

Scientia Pharmaceutica, 79(3), 525-544 (2011)

Development and validation of stability indicating assay method of cetirizine hydrochloride by HPLC.

Khan MI, et al.

African Journal of Pharmacy and Pharmacology, 5(2), 143-149 (2011)

Determination and quantification of cetirizine HCl in dosage formulations by RP-HPLC.

ARAYNE MS, et al.

Science, 1(4), 1-4 (2005)

RP-HPLC and spectrophotometric estimation of ambroxol hydrochloride and cetirizine hydrochloride in combined dosage form.

Bhatia NM, et al.

Indian Journal of Pharmaceutical Sciences, 70(5), 603-603 (2008)

Development and validation of a novel RP-HPLC method for simultaneous determination of paracetamol, phenylephrine hydrochloride, caffeine, cetirizine and nimesulide in tablet formulation.

Dewani AP, et al.

Arabian Journal of Chemistry, 8(4), 591-598 (2015)

文件