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Merck
CN

PHR1721

Supelco

特拉唑嗪

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

特拉唑嗪 盐酸盐 二水合物

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关于此项目

经验公式（希尔记法）:
C19H25N5O4 · HCl · 2H2O
CAS Number:
70024-40-7
分子量:
459.92
MDL编号:
MFCD00941408
UNSPSC代码:
41116107
PubChem化学物质编号:
329823574
NACRES:
NA.24

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等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to Ph. Eur. Y0000621
traceable to USP 1643452

API类

terazosin

CofA

current certificate can be downloaded

包装

pkg of 1 g

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

SMILES字符串

O.O.Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4

InChI

1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2

InChI key

NZMOFYDMGFQZLS-UHFFFAOYSA-N

基因信息

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

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相关类别

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Terazosin Hydrochloride belongs to the class of a1-adrenergic blockers, widely used for the treatment of benign prostatic hyperplasia (BPH) affecting the urogenital tract in men.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

It may be used as drug standard stock solution for determination of terazosin hydrochloride dihydrate using potentiometric and fluorimetric techniques.
Terazosin Hydrochloride may be used as a drug standard stock solution for the determination of terazosin hydrochloride dihydrate using potentiometric and fluorimetric techniques.
Terazosin Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance thin layer chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7395 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H319

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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Validated HPTLC method for the simultaneous determination of alfuzosin, terazosin, prazosin, doxazosin and finasteride in pharmaceutical formulations
Belal.ST, et al.
Analytical Chemistry Research, 1, 23-31 (2014)
Potentiometric and fluorimetric methods for the determination of terazosin HCl in drug substance and dosage forms.
Ismail, Nahla S., and Taghreed A. Mohamed.
International Journal of Electrochemical Science, 9, 7394-7394 (2014)
Terazosin potentiometric sensor for quantitative analysis of terazosin hydrochloride in pharmaceutical formulation based on computational study.
Hosseini, Morteza, Ensieh Nasli-Esfahani, and Parviz Norouzi.
International Journal of Electrochemical Science, 5, 200-214 (2010)

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