Merck
CN

PHR1807

Supelco

西地那非

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
西地那非 柠檬酸盐, 1-[[3-(4,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑并[4,3-d]嘧啶-5-基)-4-乙氧基苯基]磺酰基]-4-甲基哌嗪 柠檬酸盐, 5-[2-乙氧基-5-(4-甲基哌嗪-1-基)磺酰基苯基] -1-甲基-3-丙基-4H-吡唑并[5,4-e]嘧啶-7-酮 柠檬酸盐, UK-92,480, 西地那非
Empirical Formula (Hill Notation):
C22H30N6O4S ·C6H8O7
分子量:
666.70
MDL编号:
PubChem化学物质编号:

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. Y0001578
traceable to USP 1612561

API family

sildenafil

形式

solid

CofA

current certificate can be downloaded

包装

pkg of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

储存温度

2-8°C

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2C(=O)NC(=Nc12)c3cc(ccc3OCC)S(=O)(=O)N4CCN(C)CC4

InChI

1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

DEIYFTQMQPDXOT-UHFFFAOYSA-N

Gene Information

human ... PDE5A(8654)

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此商品
Y00015781612561Y0001891
Sildenafil Citrate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1807

西地那非

Sildenafil citrate European Pharmacopoeia (EP) Reference Standard

Y0001578

西地那非

Sildenafil citrate United States Pharmacopeia (USP) Reference Standard

USP

1612561

西地那非柠檬酸盐

Sildenafil for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001891

西地那非 柠檬酸盐

form

solid

form

-

form

-

form

-

packaging

pkg of 500 mg

packaging

-

packaging

-

packaging

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

一般描述

药物二级标准品CRM,为制药行业QC实验室及生产质量控制和研发,提供了一种方便、高性价比且符合相关法规的替代方案。

应用

这些二级标准品是合格的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

生化/生理作用

西地那非是cGMP特异性5型磷酸二酯酶(PDE5)的一种有效选择性抑制剂。西地那非可用于治疗勃起功能障碍和肺动脉高压。NO可激活鸟苷酸环化酶,从而导致cGMP水平增加并产生平滑肌松弛。西地那非可通过抑制负责cGMP降解的PDE5来增强NO的作用。

分析说明

这些二级标准品可溯源到USP、EP和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

欲查看此物质的分析证书样本,请在下面的“文档”框中输入LRAB9121。这只是一个示例证书,可能与您收到的批次不符。

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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