PHR1909
阿替洛尔
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
阿替洛尔, (±)-4-[2-羟基-3-[（1-甲基乙基）氨基] 丙氧基] 苯乙酰胺, 4-[2′-羟基-3′-（异丙胺基）丙氧基] 苯乙酰胺
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关于此项目
经验公式（希尔记法）:
C14H22N2O3
化学文摘社编号:
分子量:
266.34
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
249-451-7
MDL number:
产品名称
阿替洛尔, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
METKIMKYRPQLGS-UHFFFAOYSA-N
InChI
1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
SMILES string
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. A1340000
traceable to USP 1044403
API family
atenolol
form
powder
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
application(s)
pharmaceutical
storage temp.
2-30°C
Quality Level
Gene Information
human ... ADRB1(153)
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Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
This pharmaceutical secondary standard can also be used as follows:
- Simultaneous analysis of atenolol and nifedipine using magnesium oxide-nanoplatelets (MgO-NPLs) modified screen-printed electrodes (SPEs) by differential pulse voltammetry (DPV) from pharmaceutical dosage forms and urine samples
- Voltammetric determination of amlodipine besylate and atenolol in their combined pharmaceutical formulations using a cathodically pretreated-boron doped diamond electrode (CP-BDDE)
- Spectrofluorimetric determination of atenolol using gold nanoparticles (AuNPs) based photo probes in commercial tablets
- Amperometric estimation of atenolol using bismuth vanadate-bismuth(III) oxide (BiVO4–Bi2O) composite electrode in pharmaceutical formulations and human urine samples
- Development of a reversed phase-high performance liquid chromatography (RP-HPLC) method coupled to a photodiode array detector (PDA) for the quantitative analysis of atenolol and trimetazidine in human urine and pharmaceutical tablets
General description
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC0712 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Simultaneous voltammetric determination of antihypertensive drugs amlodipine and atenolol in pharmaceuticals using a cathodically pretreated boron-doped diamond electrode
Moraes JT, et al.
Journal of the Brazilian Chemical Society, 27, 1264-1272 (2016)
BiVO4-Bi2O3/ITO electrodes prepared by layer-by-layer: application in the determination of atenolol in pharmaceutical formulations and urine
Afonso R, et al.
Journal of Electroanalytical Chemistry, 765, 30-36 (2016)
Simultaneous voltammetric determination of antihypertensive drugs nifedipine and atenolol utilizing MgO nanoplatelet modified screen-printed electrodes in pharmaceuticals and human fluids
Khairy M, et al.
Sensors and Actuators B, Chemical, 252, 1045-1054 (2017)
商品
TLC plates, with silica gel, gypsum as binder, International Pharmacopoeia compliant, for identification of Atenolol and Chlorthalidone in tablets.
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