PHR2020
坎地沙坦酯相关化合物 F
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
(1-(Cyclohexyloxycarbonyloxy]ethyl 2-ethoxy-1-{[2′-(2-ethyl-2H-tetrazol-5-yl)-biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
一般描述
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Candesartan cilexetil is a selective antagonist to Angiotensin II receptors, that plays a crucial role in blood pressure regulation and sodium homeostasis, and is popularly used for the treatment of hypertension, diabetic nephropathy and congestive heart failure.
Candesartan cilexetil is a selective antagonist to Angiotensin II receptors, that plays a crucial role in blood pressure regulation and sodium homeostasis, and is popularly used for the treatment of hypertension, diabetic nephropathy and congestive heart failure.
应用
Candesartan cilexetil may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析说明
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
其他说明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB4750 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simple and sensitive LC-UV method for simultaneous analysis of hydrochlorothiazide and candesartan cilexetil in pharmaceutical formulations
Qutab SS, et al.
Acta Chromatographica , 19(12), 119-119 (2007)
Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide by High-Performance Liquid Chromatography
Khedr AE
Journal of King Abdulaziz University - Medical Sciences, 15(2), 3-13 (2008)
Characterization of conjugated metabolites of a new angiotensin II receptor antagonist, candesartan cilexetil, in rats by liquid chromatography/electrospray tandem mass spectrometry following chemical derivatization
Kondo T, et al.
Journal of Mass Spectrometry : Jms, 31(8), 873-878 (1996)
Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist
Otsuka M, et al.
Thorax, 59(1), 31-38 (2004)
A comparison of the efficacy and duration of action of candesartan cilexetil and losartan as assessed by clinic and ambulatory blood pressure after a missed dose, in truly hypertensive patients: a placebo-controlled, forced titration study
Lacourciere Y and Asmar R
American Journal of Hypertension, 12(12), 1181-1187 (1999)
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