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Merck
CN

R0300000

醋酸维生素 A

European Pharmacopoeia (EP) Reference Standard

别名:

视黄醇乙酸酯, 维生素 A 醋酸酯, 醋酸维生素 A

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关于此项目

经验公式(希尔记法):
C22H32O2
化学文摘社编号:
分子量:
328.49
Beilstein:
1915439
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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生物来源

synthetic

等级

pharmaceutical primary standard

Agency

EP

API类

retinyl compounds

表单

solid

制造商/商品名称

EDQM

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

57-58 °C

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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一般描述

本品根据现行药典要求提供和指定。所有为支持本产品而提供的信息,包括SDS和任何产品信息小册子,均根据现行药典制定和发布。更多信息和支持请访问药典颁发机构网站。

视黄醇乙酸酯属于视黄醇类,与维生素A在化学上相关。视黄醇用于通过口服和局部给药治疗痤疮和牛皮癣。

应用

本欧洲药典参考标准仅用于欧洲药典中明确规定的用途。

包装

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他说明

可能适用相应的销售限制。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 4 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Simultaneous determination of retinol acetate, retinol palmitate, cholecalciferol, α-tocopherol acetate and alphacalcidol in capsules by non-aqueous reversed-phase HPLC and column backflushing
Wielinski S and Olszanowski A
Chromatographia, 50(1-2), 109-112 (1999)
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Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
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Mice lacking retinal pigment epithelium-specific 65-kDa protein (RPE65) develop retinopathy and blindness resembling Leber congenital amaurosis. Effects of 9-cis-retinyl acetate (9-cis-R-Ac) on visual function and retinopathy progression were tested in Rpe65(-/-) mice. Young C57Bl/6 mice were given 9-cis-R-Ac in each
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A wide range of cosmeceutical products are available on the market currently, but evidence to support their use is often lacking in the literature. Specifically, there is a substantial amount of evidence supporting the efficacy of tretinoin in photoaging, but
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Exposure to bright light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental animals, but the mechanism(s) remain unclear. We investigated whether the retinoid cycle (i.e. the series of biochemical reactions required for vision through continuous generation

实验方案

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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