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Merck
CN

T1100000

Thiamphenicol

European Pharmacopoeia (EP) Reference Standard

别名:

D-threo-2,2-Dichloro-N-(β-hydroxy-α-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide

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关于此项目

经验公式(希尔记法):
C12H15Cl2NO5S
化学文摘社编号:
分子量:
356.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2819542
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产品名称

Thiamphenicol, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl

InChI key

OTVAEFIXJLOWRX-NXEZZACHSA-N

grade

pharmaceutical primary standard

API family

thiamphenicol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Thiamphenicol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[Toxicity of chloramphenicol and thiamphenicol (CAP and TAP)].
G Keiser
Haematology and blood transfusion, 21, 179-195 (1978-01-01)
D Malvy et al.
Intensive care medicine, 18(8), 485-487 (1992-01-01)
A 27-year-old woman, without compromised immunodefenses, experienced a Listeria meningoencephalitis, with brainstem symptoms. The identified agent exhibited poor susceptibility to usual effective antibiotics, except for penicillins. Knowledge of past history of an allergic reaction to beta-lactam antibiotics lead to appropriate
J Raymond et al.
Medecine tropicale : revue du Corps de sante colonial, 64(1), 33-38 (2004-07-01)
Streptococcus pneumoniae and Haemophilus influenzae are the two main pathogens responsible for bacterial respiratory tract infections. Their antimicrobial susceptibility to antibiotics like beta-lactams, macrolides or fluoroquinolones has been largely studied, while it remains less known to other antibiotics like thiamphenicol
Chloramphenicol and thiamphenicol.
J Fuglesang et al.
Antibiotics and chemotherapy, 31, 1-21 (1982-01-01)
[Chloramphenicol and thiamphenicol].
L Mariani
La Clinica terapeutica, 86(3), 195-218 (1978-08-15)

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