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Merck
CN

V0030000

缬氨酸

European Pharmacopoeia (EP) Reference Standard

别名:

L -缬氨酸, (S)-α-缬氨酸, L-2-氨基-3-二甲基丁酸

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关于此项目

线性分子式:
(CH3)2CHCH(NH2)CO2H
化学文摘社编号:
分子量:
117.15
Beilstein:
1721136
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

valine

制造商/商品名称

EDQM

mp

295-300 °C (subl.) (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC(C)[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

InChI key

KZSNJWFQEVHDMF-BYPYZUCNSA-N

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一般描述

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

应用

缬氨酸EP参考标准品的预期用途是欧洲药典规定的实验室测试。

包装

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他说明

可能适用相应的销售限制。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Growth inhibition as a consequence of antagonism between related amino acids: effect of valine in Escherichia coli K-12.
M De Felice et al.
Microbiological reviews, 43(1), 42-58 (1979-03-01)
Xin Zhang et al.
Hypertension (Dallas, Tex. : 1979), 64(1), 87-93 (2014-04-23)
Renovascular hypertension alters cardiac structure and function. Autophagy is activated during left ventricular hypertrophy and linked to adverse cardiac function. The angiotensin II receptor blocker, valsartan, lowers blood pressure and is cardioprotective, but whether it modulates autophagy in the myocardium
Thomas D Giles et al.
Lancet (London, England), 383(9932), 1889-1898 (2014-06-03)
The fixed-dose combination of any two antihypertensive drugs from different drug classes is typically more effective in reducing blood pressure than a dose increase of component monotherapy. We assessed the efficacy and safety of a fixed-dose combination of a vasodilating
K Aaboe et al.
Diabetes, obesity & metabolism, 17(1), 74-81 (2014-09-23)
To examine whether 12 weeks of treatment with a dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin, influences the insulin secretion induced by glucose, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) during a hyperglycaemic clamp in patients with type 2 diabetes (T2DM).
Armin H Seidl et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(14), 4914-4919 (2014-04-04)
Information processing in the brain relies on precise timing of signal propagation. The highly conserved neuronal network for computing spatial representations of acoustic signals resolves microsecond timing of sounds processed by the two ears. As such, it provides an excellent

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